Effects of Developmental Stage and Transitions on Drug Use Trajectories

项目描述：本研究的主要目的是研究发育阶段和过渡阶段对药物使用轨迹的影响，并为设计预防方案提供启示，预防方案适用于成年初显期和成年早期，这是一个相对较少研究的预防人群。利用纵向随机药物使用预防试验中收集的大型城市人口代表性样本（N=1206, 50%女性，40%中低收入，75%白人）的数据，该研究将进行二次数据分析，以了解四个不同发育时期药物使用风险的变化和预测这些变化的变量：青春期早期（P1：中学，或12-14岁），青春期晚期（P2：高中，或15-18岁），成年初期（P3: 15-18岁）。年龄19-25岁)和成年期（P4: 25岁以上），特别关注新成年期过渡作为药物使用调节因素的影响。拟议的研究还将确定中介变量，特别是那些干预计划的目标变量，是否已经被发现影响青少年时期的吸毒风险，对成年期的吸毒有持续的中介关系，以及这些相同的变量是否与成年期的过渡有关。拟建项目的目标是：1。研究青少年早期到成年期一系列发育阶段中药物使用的增长轨迹；2. 确定与不同发育时期药物使用增长轨迹相关的保护因素和风险因素；3. 探讨年龄/阶段转换、社会生活事件转换和环境生活事件转换对初成年期物质使用行为的调节作用；以及一个探索性的目标4。确定从青春期早期到成年初期具有更突出的药物使用风险轨迹的个体亚组。最先进的以及新的探索性变化的增长曲线模型将用于测试这些关系。这项研究预计将为制定针对吸毒风险变化的年轻人的加强和量身定制的预防方案提供重要方向。研究结果应该推广到城市地区的年轻人。

DESCRIPTION (provided by applicant): Effects of Developmental Stage and Transitions on Drug Use trajectories Project Description: The major goal of the proposed study is to investigate the effects of developmental stage and transitions on drug use trajectories, with implications for designing prevention programs for the emerging adulthood and early adulthood periods, a relatively understudied population for prevention. Using data collected on a large urban population-representative sample (N=1206, 50% female, 40% low-moderately low income, 75% white) from a longitudinal randomized substance use prevention trial, the study will conduct secondary data analyses to understand shifts in drug use risk and variables predictive of these shifts over four different developmental periods: early adolescence (P1: middle school, or age 12-14), late adolescence (P2: high school, or age 15-18), emerging adulthood (P3: age 19-25) and adulthood (P4: older than age 25), with a particular focus on the impact of emerging adulthood transitions as moderators of drug use. The proposed study will also determine whether mediating variables, especially those targeted by the intervention program, that have been previously found to affect drug use risk through the adolescent years have a sustained mediational relationship to drug use in adulthood, and whether these same variables are associated with emerging adulthood transitions. The aims of the proposed project are: 1. To examine the growth trajectories of substance use in a series of developmental periods from early adolescence to adulthood; 2. To identify protective and risk factors associated with the growth trajectories of substance use during different developmental periods; 3. To investigate moderation impacts of age/stage-based transition, social life event transition and environmental life event transition on substance use behavior during emerging adulthood; and an exploratory Aim 4. To identify subgroups of individuals with more salient drug use risk trajectories from early adolescence to emerging adulthood. State-of-the-art as well as new exploratory variations of growth curve modeling will be used to test these relationships. The study is expected to yield important directions for developing booster and tailored prevention programs for young adults who are identified by shifts in drug use risk. The findings should generalize to young adult populations from urban areas. PUBLIC HEALTH RELEVANCE: The present project focuses on increasing our understanding of the relationships of substance use and risk trajectories to developmental stages and transitions, over a life span covering early adolescence to early adulthood (from age 11 to 30). The proposed study will use a longitudinal randomized prevention trial data set with 14 waves of data collected between 1987 and 2005 to investigate the relationships of substance use trajectories in different developmental periods and identify critical factors associated with substance use at each period. Findings are expected to inform the development of targeted prevention programs for young adults, a population relatively understudied in prevention, and thus potentially constituting a specialized health disparities group.