Regulation of Estrogen Receptor Target Genes by the Pioneer Factor GATA4 in Bone

骨中先锋因子 GATA4 对雌激素受体靶基因的调节

• 批准号: 8145771
• 负责人: Susan A Miranda
• 金额: $ 19.25万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8145771
• 关键词: Affect; Binding; Binding Sites; Biological Assay; Biology; Bone Density; Bone Development; Boxing; Cell Line; Cells; Complex; DNA; DNA-Binding Proteins; Data; Development; Disease; Elements; Enhancers; Estradiol; Estrogen Receptor 1; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptors; Estrogens; Female; GATA4 transcription factor; Gene Expression; Gene Expression Regulation; Gene Targeting; Genes; Genetic Transcription; Goals; Homeostasis; Human; Immune; In Vitro; Indium; Knock-out; Maintenance; Mammary Gland Parenchyma; Mediating; Minerals; Modeling; Mus; Nuclear Receptors; Nucleic Acid Regulatory Sequences; Osteoblasts; Osteoporosis; Osteoporosis prevention; Play; Population; Process; Proteins; Public Health; Recruitment Activity; Regulation; Role; Skeleton; Testing; Therapeutic; Time; Tissues; Transcription Factor AP-2 Gamma; United States; activator 1 protein; aging population; bone; bone cell; cell type; chromatin immunoprecipitation; chromatin remodeling; design; in vivo; malignant breast neoplasm; mineralization; novel; osteoblast differentiation; protective effect; protein complex; public health relevance; reproductive; research study; transcription factor