Dissecting PKC-theta-regulated T cell functions in allograft rejection

剖析 PKC-theta 调节的 T 细胞在同种异体移植排斥反应中的功能

• 批准号: 8123649
• 负责人: Zuoming Sun
• 金额: $ 41.5万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8123649
• 关键词: Achievement; Acute; Adoptive Transfer; Apoptosis; Apoptotic; Autoantigens; Autoimmunity; B-Lymphocytes; Basic Science; Bone Marrow Transplantation; CD28 gene; Cell Survival; Cell physiology; Cellular biology; Cities; Clinical; Collaborations; Comprehensive Cancer Center; Data; Development; Drug Delivery Systems; Environment; Financial compensation; Goals; Graft Rejection; Heart; Heart Transplantation; Heating; Immune response; Immune system; Knowledge; Learning; Ligands; Lupus Erythematosus; Mediating; Mediator of activation protein; Modeling; Molecular; Mus; Organ Transplantation; Outcome; Pathway interactions; Patients; Peripheral; Pharmaceutical Preparations; Prevention; Prevention strategy; Protein Kinase; Protein Kinase C; Publications; Rag1 Mouse; Receptor Signaling; Regulation; Research; Research Institute; Rheumatoid Arthritis; Role; Signal Pathway; Signal Transduction; T-Cell Receptor; T-Lymphocyte; Testing; Therapeutic; Thymus Gland; Translational Research; Transplantation; Up-Regulation; Work; Yin; allograft rejection; base; clinical application; experience; heart allograft; in vivo; inhibitor/antagonist; innovation; novel; prevent; pro-apoptotic protein; public health relevance; therapeutic development