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Dissecting PKC-theta-regulated T cell functions in allograft rejection

Dissecting PKC-theta-regulated T cell functions in allograft rejection
剖析 PKC-theta 调节的 T 细胞在同种异体移植排斥反应中的功能
批准号：
8123649
负责人：
Zuoming Sun
金额：
$41.5万
依托单位：
BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-09-01 至 2012-08-31
来源：
https://reporter.nih.gov/project-details/8123649
关键词：
AchievementAcuteAdoptive TransferApoptosisApoptoticAutoantigensAutoimmunityB-LymphocytesBasic ScienceBone Marrow TransplantationCD28 geneCell SurvivalCell physiologyCellular biologyCitiesClinicalCollaborationsComprehensive Cancer CenterDataDevelopmentDrug Delivery SystemsEnvironmentFinancial compensationGoalsGraft RejectionHeartHeart TransplantationHeatingImmune responseImmune systemKnowledgeLearningLigandsLupus ErythematosusMediatingMediator of activation proteinModelingMolecularMusOrgan TransplantationOutcomePathway interactionsPatientsPeripheralPharmaceutical PreparationsPreventionPrevention strategyProtein KinaseProtein Kinase CPublicationsRag1 MouseReceptor SignalingRegulationResearchResearch InstituteRheumatoid ArthritisRoleSignal PathwaySignal TransductionT-Cell ReceptorT-LymphocyteTestingTherapeuticThymus GlandTranslational ResearchTransplantationUp-RegulationWorkYinallograft rejectionbaseclinical applicationexperienceheart allograftin vivoinhibitor/antagonistinnovationnovelpreventpro-apoptotic proteinpublic health relevancetherapeutic development

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