Targeting T lymphocyte potassium channels for the treatment of asthma--OLD

靶向T淋巴细胞钾通道治疗哮喘--OLD

• 批准号: 8122828
• 负责人: Christine Beeton
• 金额: $ 38.38万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-18 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8122828
• 关键词: Affect; Affinity; Animal Model; Animals; Asthma; Autoimmune Diseases; Bacterial Infections; Biological Assay; Biological Availability; Blood; Cells; Chronic; Chronic Disease; Confocal Microscopy; Cytoplasmic Granules; Data; Delayed Hypersensitivity; Development; Disease; Extrinsic asthma; Flow Cytometry; Frequencies; Goals; Human; Immune; Immunosuppression; In Vitro; Incidence; Inflammatory; Insulin-Dependent Diabetes Mellitus; Ion Channel; Kv1.3 potassium channel; Lung; Lymphocyte; Lymphocyte Activation; Mediating; Memory; Mucous body substance; Multiple Sclerosis; Pathogenesis; Patients; Phenotype; Play; Population; Potassium; Potassium Channel; Prevalence; Prevention; Production; Proliferating; Public Health; Rheumatoid Arthritis; Role; Sampling; Severities; Signal Transduction; Sputum; Structure of parenchyma of lung; Synapses; T-Lymphocyte; T-Lymphocyte Subsets; Testing; Therapeutic; Toxic effect; Tumor Necrosis Factor Ligand Superfamily Member 6; Viral; airway hyperresponsiveness; asthmatic patient; cell motility; channel blockers; cytokine; cytotoxic; healthy volunteer; immunoregulation; in vivo; killer T cell; killings; new therapeutic target; patch clamp; prevent; public health relevance; research study; synaptogenesis; terminally differentiated effector memory (TEM) T cells; therapeutic target