GENETICS OF WHITE MATTER DEFICITS IN SCHIZOPHRENIA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是研究精神障碍患者和健康志愿者的大脑结构和功能指标与遗传变异之间的关系。特别是，我们将确定精神分裂症患者和健康志愿者脑白质结构相关基因与体内脑白质完整性测量之间的关系。档案数据将通过IRB批准的名为“精神病患者和健康志愿者的磁共振成像(MRI)扫描数据存储库”的协议获得。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aim of this study is to examine the relationship between genetic variation and measures of brain structure and function in individuals with psychiatric disorders and healthy volunteers. In particular, we will determine the relationship between genes associated with white matter structure and in-vivo measures of brain white matter integrity in patients with schizophrenia and healthy volunteers. Archival data will be obtained through the IRB-approved protocol entitled "Data repository for Magnetic Resonance Imaging (MRI) Scans of Psychiatric Patients and Healthy Volunteers."