ENDOSCOPIC ASSESSMENT OF SWALLOWING IN HEALTHY ADULTS - GCRC PILOT STUDY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 20年来，它一直是60多篇同行评审出版物中的吞咽评估工具。然而，令人惊讶的是，很少有数据存在正常的吞咽评估内窥镜。我们的长期目标是获得广泛的规范性数据，吞咽内镜评估，并获得全面的数据之间和内部评级的可靠性，我们选择的内镜吞咽措施。我们的长期目标是获得广泛的规范性数据，吞咽内镜评估，并获得全面的数据之间和内部评级的可靠性，我们选择的内镜吞咽措施。然而，对于R 03赠款申请，有两个具体的目标，将获得初步/试点数据，以实现我们的长期目标。 具体目标该资助之一需要四个独立的实验来确定七个不同因素/问题对内窥镜吞咽测量的影响。 具体目标2将确定在20%的分层数据上选择的四种吞咽内镜测量的评估者间和评估者内可靠性，以代表不同年龄和丸剂类型。将根据短期和长期重复评级评估评估者内可靠性。评估者间可靠性将根据临床医生FEES经验的三个水平进行评估（即，初级、中级和高级）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 20 years and it has been the swallowing evaluation tool in over 60 peer-reviewed publications. However, amazingly scant data exists on normal swallowing as assessed endoscopically. Our long-range objectives are to obtain extensive normative data on swallowing as assessed endoscopically and to obtain comprehensive data on the inter- and intra-rater reliability of the endoscopic swallowing measures we have chosen. Our long-range objectives are to obtain extensive normative data on swallowing as assessed endoscopically and to obtain comprehensive data on the inter- and intra-rater reliability of the endoscopic swallowing measures we have chosen. However, for this R03 grant application, there are two specific aims that will obtain preliminary/pilot data towards our long-range objectives. Specific Aim One of this grant requires four separate experiments to determine the effects of seven different factors/issues on endoscopic swallowing measurements. Specific Aim Two will determine the inter- and intra-rater reliability of the four endoscopic measurements of swallowing chosen on 20% of the data stratified to represent various ages and bolus types. Intra-rater reliability will be assessed as a function of short- and long-term repeat ratings. Inter-rater reliability will be assessed as a function of three levels of clinician FEES experience (i.e., beginning, intermediate, and advanced) across nine independent raters without pre-training.