RESPONSE OF SERUM 25-HYDROXYVITAMIN D TO INCIDENTAL UV LIGHT EXPOSURE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 这项研究正在研究血液中维生素D水平的变化对人们每天暴露在阳光下的反应。 众所周知，来自太阳的紫外线可以刺激人体产生活性形式的维生素D，它具有许多对我们健康至关重要的功能。众所周知，暴露在阳光下与某些类型的皮肤癌的发展直接相关。 虽然维生素D可以在某些食物和膳食补充剂中找到，但有人认为，阳光产生的维生素D对维持我们体内的健康水平至关重要。 以前没有研究测量我们的身体对来自太阳的紫外线的测量量做出反应时产生的维生素D的量。 到目前为止，只有估计的阳光量被认为是获得特定数量的维生素D所必需的。 这项研究将提供数据，可以更准确地证明有多少维生素D是在体内产生的，以响应每天暴露在阳光下。 然后，可以建议最小限度地暴露在阳光下，充分增加维生素D的水平，同时避免增加皮肤癌风险的过度暴露时间。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This research is studying the change in the level of vitamin D in the blood in response to peoples daily exposure to sunlight. Ultraviolet rays from the sun are known to stimulate the body to produce the active form of vitamin D which serves many functions necessary to our health. It is also known that exposure to sunlight is directly related to the development of certain types of skin cancer. Although vitamin D can be found in certain foods and dietary supplements, it has been argued that the vitamin D produced by sunlight is essential to maintaining healthy levels in our bodies. There are no previous studies measuring the amount of vitamin D that is produced by our bodies in response to a measured quantity of ultraviolet light from the sun. To date, there are only estimated amounts of sunlight that are considered necessary to obtaining specific amounts of vitamin D. This study will provide data that can more accurately demonstrate how much vitamin D is produced in the body in response to everyday exposure to the sun. It may then be possible to recommend minimal exposure to sunlight that adequately increases levels of vitamin D while avoiding excessive exposure times that increase the risk of skin cancer.