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Establishment of HIV infection and ensuing HostiVirus interactions

Establishment of HIV infection and ensuing HostiVirus interactions
HIV 感染的建立和随后的 HostiVirus 相互作用
批准号:
7854603
负责人:
JAMES Ivan MULLINS
金额:
$66.83万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-07-15 至 2015-06-30
关键词:
AIDS vaccine developmentAcuteAddressAffectAgreementAllelesAmino AcidsAntigensAutologousAutomobile DrivingBackBarrier ContraceptionBioinformaticsBiologicalBiological AssayBlood specimenCD4 Positive T LymphocytesCD8B1 geneCell Culture TechniquesCellsCharacteristicsChimera organismChronicChronic PhaseClinic VisitsCodeCohort StudiesCytotoxic T-LymphocytesDNA biosynthesisDataDatabasesDefectDetectionDisease ProgressionEnrollmentEpidemicEpitopesEscape MutantEvaluationEventEvolutionFigs - dietaryFlow CytometryFoundationsFounder GenerationFrequenciesFunctional disorderFundingFutureGaggingGenesGeneticGenetic VariationGenotypeGerda brand of difluprednateGoalsGrantGrowthHIVHIV Envelope Protein gp120HIV InfectionsHIV-1IL2 geneImmuneImmune TargetingImmune responseImmunologic FactorsImmunologicsIndividualInfectionInstitutesInterleukin-10LengthLightLinkLiteratureMeasuresMechanicsMethodsMinorMinorityMolecularMono-SMutateMutationNatural ImmunityPeptidesPeripheralPeripheral Blood Mononuclear CellPersonsPhenotypePhylogenetic AnalysisPlasmaPopulationProliferatingProteinsProteolytic ProcessingProteomeRelative (related person)Research PersonnelResistanceRoleSamplingSecondary toSerumShapesSiteSite-Directed MutagenesisSourceSpecificitySpecimenT-LymphocyteT-Lymphocyte EpitopesTechnologyTestingTimeUniversitiesVaccine DesignVaccinesVariantVertebral columnViralViral GenesViral GenomeViremiaVirusbasecell typecellular targetingcostcytokinedesigndriving forceenv Gene Productsfitnessfollow-upgenetic analysisgenetic evolutiongenome sequencingimprovedinsightkillingslongitudinal analysismacrophagemutantperforinpressurepreventprogramsresponsesample fixationtransmission processvirus genetics

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中文摘要
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英文摘要
Using linked HIV-1 transmission partner pairs. Project 1 will define the eariiest events in the establishment of HIV-1 infection, focusing on the interacfions between CTL responses and viral evolufion and fitness.
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Role of proviral loci in HIV latency
  • 批准号:
    9330768
  • 项目类别:
  • 资助金额:
    $85.22万
  • 财政年份:
    2016
  • 负责人:
    JAMES Ivan MULLINS
  • 依托单位:
Ex Vivo Detection and Analysis of Non-inducible Latent HIV
  • 批准号:
    9046237
  • 项目类别:
  • 资助金额:
    $23.64万
  • 财政年份:
    2015
  • 负责人:
    JAMES Ivan MULLINS
  • 依托单位:
Ex Vivo Detection and Analysis of Non-inducible Latent HIV
  • 批准号:
    9187886
  • 项目类别:
  • 资助金额:
    $24.21万
  • 财政年份:
    2015
  • 负责人:
    JAMES Ivan MULLINS
  • 依托单位:
Mechanisms of Formation and Persistence of Active HIV Reservoirs
  • 批准号:
    9229518
  • 项目类别:
  • 资助金额:
    $85.28万
  • 财政年份:
    2014
  • 负责人:
    JAMES Ivan MULLINS
  • 依托单位:
海外基金