University of Rochester Child Neurology Academic Development Program

项目概述：罗彻斯特大学儿童神经病学职业发展计划将为有前途的儿童神经病学初级教师提供正式的基于项目的职业发展支持。我们的目标是：1)让这个项目的初级教师有机会从受指导的学员过渡到临床和/或基础神经生物学研究的独立研究者；2)培养思维能力和知识基础，使被支持的候选人能够应用基本的神经生物学原理来实现对疾病的机械理解，从而将其转化为神经系统发育障碍的治疗和诊断方案；3)通过为神经生物学科学合理、合乎伦理和临床相关的研究提供必要的指导和框架，并为儿童神经病学学术领域的未来领导者提供长期决策和职业规划所需的指导，从而促进这些初级教师的学术生涯。这些目标将在一个为期3年的项目中实现，该项目为候选人提供必要的技能，以制定与疾病相关的研究计划，并在研究成功和指导卓越的教师的指导下设计实施策略。所有支持的候选人将参加有关研究伦理、职业发展、拨款写作和科学交流的正式培训。目标是为支持的初级教员提供必要的技能，以建立神经科学的研究生涯，并作为一名有活力的专业成长承诺的研究者走向独立资助。寻求3个职位的支持，每个职位的支持期为三年。培训设施包括：神经内科、小儿科、神经生物学与解剖学、生理与药理学、脑与认知科学系的实验室，以及神经发育与疾病中心。该项目将充分利用大学临床和转化研究所的资源和职业发展基础设施，包括获得生物统计学、流行病学和临床研究专业知识，以及在学术和行业孵化器环境中开发的尖端新技术。

DESCRIPTION (provided by applicant): Project Summary: The University of Rochester Child Neurology Career Development Program will provide formal program- based career development support for promising junior faculty in child neurology. Our aims are: 1) to give junior faculty in this program the opportunity to transition from mentored trainees to independent investigators in clinical and/or basic neurobiology research; 2) to foster thinking skills and a knowledge base that will allow supported candidates to apply basic neurobiological principles to achieve a mechanistic understanding of disease so they can translate them into therapeutic and diagnostic options for disorders of the developing nervous system; 3) to foster the academic careers of these junior faculty by providing the guidance and framework necessary for the conduct of scientifically sound, ethical, and clinically relevant research in neurobiology with the mentoring necessary for long-term decision-making and career planning as future leaders in academic child neurology. These goals will be achieved during a 3-year program that provides the candidates with the necessary skills to formulate a research plan relevant to disease and design an implementation strategy under the guidance of faculty who have demonstrated research success and mentoring excellence. All supported candidates will participate in formal training in research ethics, career development, grant writing, and scientific communication. The goal is to provide the supported junior faculty members with the skills necessary to establish a research career in neurological science and to move toward independent funding as an investigator with the promise of vigorous professional growth. Support is sought for 3 positions, each for a three year period of support. Training facilities include: laboratories in the departments of Neurology, Pediatrics, Neurobiology & Anatomy, Physiology & Pharmacology, Brain & Cognitive Sciences, and the Center for Neural Development and Disease. The program will take full advantage of the resources and career development infrastructure of the UR Clinical and Translational Research Institute, including access to biostatistical, epidemiologic, and clinical research expertise and cutting-edge novel technologies developed in both academic and industry incubator settings. Public Health Relevance: It is increasingly difficult to attract, foster, and maintain a cadre of child neurologists whose interests are in the development of a translational body of knowledge and the dialogue between the laboratory bench and the clinic. This program will support the career development of talented individuals dedicated to academic research careers researchers at the interface between neurological sciences and child neurology.