Explosive Evolution Under Stress: The Driving Forces of Cancer Dynamics (Main)

描述(由申请人提供)：中心组织和基础设施代表该PS-OC的运营骨干。它将提供总体通信网络、管理结构、行政支持、财政监督以及与中心所有项目和核心的联系。它将协调所有项目会议、内部和外部委员会的会议，这些委员会是中心的一部分，并与网络的其他PS-OCS连接。它将生成进度报告--既有科学的，也有财务的--提交给NCI，并将监督每个项目的预算以及与试点项目和跨网络项目有关的活动。中心管理团队将保存所有项目会议的记录，并将为中心的项目和其他关键职能提供特别支持或解决问题的能力。将通过定期安排调查人员和工作人员会议以及定期举行科学务虚会，鼓励和促进调查人员之间和项目之间的合作。将通过集中簿记职能、协调手稿准备以及规划旅行和研究小组会议来促进行政活动。中心的管理机构将由中心首席调查员、联合首席调查员、中心行政主任、中心教育培训和推广活动主任以及4个技术项目的负责人组成。该团队将与中心管理委员会密切合作，首席调查员和合作伙伴将代表中心参加PS-OC网络指导委员会。资助哪些试点项目，实现哪些跨网络项目，将由中心领导、管理和咨询委员会成员共同协商一致决定。

DESCRIPTION (provided by applicant): The Center Organization and Infrastructure represents the operational backbone of this PS-OC. It will provide the overall communications network, management structure, administrative support, fiscal oversight, and linkage to all the projects and cores of the center. It will coordinate all project meetings, meetings of the internal and external committees which are part of the center and interface with other PS-OCs of the network. It will generate progress reports - both scientific and fiscal - for submission to NCI and will oversee the budget of each project and activities related to pilot and trans-network projects. The center Administrative team will maintain minutes of all Project meetings and will provide ad hoc support or problem-solving capability for Projects and others critical functions of the center. Collaborations between investigators and between projects will be encouraged and fostered through regularly scheduled meetings of the investigators and staff and by holding periodic scientific retreats. The administrative activities will be facilitated by centralizing bookkeeping functions, coordinating manuscript preparation, and planning travel and research group meetings. The management body of the center will consist of the Principal Investigator, Co-Principal Investigator, center administrative director, director of the education & training and outreach & dissemination activities of the center and the leaders of each of the 4 technical projects. This team will work closely the center administrative committee and the Principal Investigator and Co-Pl will represent the center on the PS-OC network steering committee. Decisions of what pilot projects are funded and what trans-network projects are realized will be made from a joint consensus of members of the center leadership & management and advisory committees.