Explosive Evolution Under Stress: The Driving Forces of Cancer Dynamics (Main)

描述（由申请人提供）：中心组织和基础设施代表了该PS-OC的运营骨干。它将为该中心的所有项目和核心提供整体通信网络、管理结构、行政支持、财政监督和联系。它将协调所有项目会议，内部和外部委员会的会议，这些会议是中心的一部分，并与网络的其他ps - oc接口。它将编制科学和财政进展报告，提交给NCI，并将监督每个项目的预算以及与试点和跨网络项目有关的活动。中心行政团队将保存所有项目会议记录，并为项目和中心的其他关键职能提供特别支持或解决问题的能力。将通过定期安排的调查人员和工作人员会议以及定期举行科学务虚会，鼓励和促进调查人员之间和项目之间的合作。行政活动将通过集中记帐职能、协调手稿编写、规划旅行和研究小组会议而得到便利。中心的管理机构将由首席研究员、联合首席研究员、中心行政主任、中心教育培训和推广活动主任以及4个技术项目的负责人组成。该团队将与中心管理委员会密切合作，首席研究员和合作伙伴将代表中心参加PS-OC网络指导委员会。资助哪些试点项目以及实现哪些跨网络项目的决定将由中心领导和管理委员会以及咨询委员会的成员共同达成共识。

DESCRIPTION (provided by applicant): The Center Organization and Infrastructure represents the operational backbone of this PS-OC. It will provide the overall communications network, management structure, administrative support, fiscal oversight, and linkage to all the projects and cores of the center. It will coordinate all project meetings, meetings of the internal and external committees which are part of the center and interface with other PS-OCs of the network. It will generate progress reports - both scientific and fiscal - for submission to NCI and will oversee the budget of each project and activities related to pilot and trans-network projects. The center Administrative team will maintain minutes of all Project meetings and will provide ad hoc support or problem-solving capability for Projects and others critical functions of the center. Collaborations between investigators and between projects will be encouraged and fostered through regularly scheduled meetings of the investigators and staff and by holding periodic scientific retreats. The administrative activities will be facilitated by centralizing bookkeeping functions, coordinating manuscript preparation, and planning travel and research group meetings. The management body of the center will consist of the Principal Investigator, Co-Principal Investigator, center administrative director, director of the education & training and outreach & dissemination activities of the center and the leaders of each of the 4 technical projects. This team will work closely the center administrative committee and the Principal Investigator and Co-Pl will represent the center on the PS-OC network steering committee. Decisions of what pilot projects are funded and what trans-network projects are realized will be made from a joint consensus of members of the center leadership & management and advisory committees.