Low-Dose High-Resolution Dental Radiography

低剂量高分辨率牙科射线照相

• 批准号: 8137816
• 负责人: NEAL EUGENE HARTSOUGH
• 金额: $ 51.64万
• 依托单位: DXRAY, INC.
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-16 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8137816
• 关键词: Animals; Area; Cardiac; Characteristics; Charge; Collaborations; Collection; Crystallography; Dental; Dental Radiography; Dental Schools; Dentists; Deposition; Development; Devices; Dose; Electronics; Equipment; Feasibility Studies; Film; Generations; Goals; Image; Legal patent; Licensing; Life; Light; Manufacturer Name; Marketing; Measures; Medicine; Modification; Mus; Output; Patients; Performance; Phase; Process; Property; Proteins; Resolution; Semiconductors; Signal Transduction; Silicon; Structure; System; Techniques; Technology; Temperature; Testing; Thick; Time; Vendor; Work; base; cost; design; design and construction; detector; digital; digital imaging; imaging detector; improved; innovation; interest; operation; patient safety; pressure; programs; prototype; public health relevance; red mercuric iodide; response; seal; sensor; technology development

DESCRIPTION (provided by applicant): We are developing a high-resolution, low-dose, direct-conversion digital x-ray detector for intraoral dental radiography. The detector will improve intraoral dental imaging with reduced dose, high resolution, and low detector cost. It can be incorporated into existing dental radiography equipment, replacing film-based or scintillator-based systems. The dose efficiency of current scintillator-CCD or scintillator-CMOS photodiode array x-ray detectors is compromised by inefficient conversion of x-rays to light, transport of the light to the detector, and conversion of the light to electric signal. We have successfully developed a new direct x-ray converter material, polycrystalline mercuric iodide (HgI2), which is a high-Z large- bandgap compound semiconductor with outstanding charge collection properties. The proposed detector is a thin film of polycrystalline mercuric iodide for direct conversion of incident x-rays into charge, grown directly onto a CMOS readout. Dose reduction will be achieved due to the very high sensitivity of mercuric iodide films. We expect to sell or license our detector technology to existing intraoral dental imaging equipment vendors. In Phase I of the project, we grew polycrystalline HgI2 directly onto our small- area CMOS readout chip, which we specially designed for compatibility with HgI2. We measured the imaging performance of the prototype device. In this Phase II we will scale the CMOS chip up to dental Size 2, place the CMOS readout into a package suitable for intraoral use, further modify the HgI2 deposition to improve spatial resolution, and complete and test a full product prototype. The product we will develop will help dentists detect hairline cracks and other high-resolution features while patients will benefit from a reduced lifetime x-ray dose. PUBLIC HEALTH RELEVANCE: We will produce an improved x-ray detector for intraoral dental radiography. The detector will reduce the x-ray dose that dental patients receive during their exam while providing dentists with high resolution images at a low cost. The semiconductor-based detector can be incorporated into existing dental radiography equipment, replacing film-based or scintillator-based systems.

描述(申请人提供)：我们正在开发一种用于口腔内牙科摄影的高分辨率、低剂量、直接转换的数字x射线探测器。该探测器将以更低的剂量、更高的分辨率和更低的探测器成本来改善口腔内的牙科成像。它可以被整合到现有的牙科放射摄影设备中，取代基于胶片或闪烁体的系统。目前的闪烁体-CCD或闪烁体-CMOS光二极管阵列X射线探测器的剂量效率受到X射线到光的低效转换、光到探测器的传输以及光到电信号的转换的影响。我们成功地研制出了一种新的直接X射线转换材料--多晶碘化汞(HgI2)，它是一种具有优异电荷收集性能的高Z大禁带化合物半导体。所提出的探测器是一种多晶碘化汞薄膜，用于将入射X射线直接转换为电荷，直接生长到cmos读出器上。由于高灵敏度的碘化汞薄膜，剂量将会减少。我们希望将我们的探测器技术出售或授权给现有的口腔内牙科成像设备供应商。在该项目的第一阶段，我们将多晶HgI2直接生长到我们专门设计的与HgI2兼容的小面积CMOS读出芯片上。对样机的成像性能进行了测试。在第二阶段中，我们将把芯片尺寸扩大到牙齿尺寸2，将读数放入适合口腔内使用的封装中，进一步修改HgI2沉积以提高空间分辨率，并完成和测试完整的产品原型。我们将开发的产品将帮助牙医检测细微裂缝和其他高分辨率功能，同时患者将受益于终身X射线剂量的减少。 公共卫生相关性：我们将生产一种改进的用于口腔内牙科X光照相的X射线探测器。该探测器将减少牙科患者在检查期间接受的X射线剂量，同时以低成本为牙医提供高分辨率图像。这种基于半导体的探测器可以集成到现有的牙科放射照相设备中，取代基于胶片或闪烁体的系统。