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Study of DDT and loss of clinically-recognized pregnancies in South Africa

Study of DDT and loss of clinically-recognized pregnancies in South Africa
南非 DDT 与临床认可妊娠流产的研究
批准号:
8149124
负责人:
Matthew Longnecker
金额:
$2.97万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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中文摘要
翻译
这项与接触滴滴涕有关的早孕流产(流产和死产)前瞻性研究的实地工作已经开始。 2010年初,一个实地小组被雇用和培训,6月1日开始招生。 正在从南非林波波省的6个村庄招募受试者,其中3个村庄目前正在使用滴滴涕控制疟疾。截至8月31日,已对209例受试者进行了合格性评价,181例入组。 大约一半的受试者来自喷洒过滴滴涕的那些村庄。 在这181人中,有8人被撤回,主要是因为他们谎报了自己居住的村庄。 在随访的172例受试者中,3例妊娠。 因此,实地工作运作良好。 目前的研究设计是否会产生足够数量的妇女在登记时怀孕,以及登记的受试者是否有适当广泛的滴滴涕接触分布,仍有待观察。
英文摘要
The field work has begun for this prospective study of early pregnancy loss (miscarriage and stillbirth) in relation to DDT exposure. A field team was hired and trained in early 2010, and enrollment began June 1. Subjects are being enrolled from 6 villages in Limpopo Province, South Africa, and DDT is currently in use for malaria control in 3 of them. As of August 31, 209 subjects have been evaluated for eligibility, and 181 were enrolled. About half of the enrolled subjects are from the villages sprayed with DDT. Of the 181, 8 were withdrawn, primarily because they had misrepresented their village of residence. Of the 172 subjects being followed, 3 have become pregnant. Thus, the field work is functioning well. Whether the present study design will yield adequate numbers of women who become pregnant while enrolled remains to be seen, as does whether the subjects enrolled have a suitably wide distribution of exposure to DDT.
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