Boston University Inflammatory Disorders Training Grant

描述（由申请人提供）：拟建的培训项目将为具有扎实免疫学学术背景的博士生和博士后提供培训，重点是多学科方法研究炎症的常见机制。培训将包括相关课程，定期安排的研讨会和期刊俱乐部，以及严格的实验室培训，目的是为我们的学员准备与本计划目标相关的研究职业。波士顿大学拥有一批对炎症性疾病长期感兴趣的优秀教师，他们是波士顿大学炎症性疾病培训计划（BU-TPID）的成员。此外，最近的招聘工作已经形成了一个临界质量的成熟的研究人员，因此，本申请建议建立一个综合培训计划的博士生和博士后研究炎症性疾病。除了他们共同的研究兴趣之外，这些院系中的许多院系已经有了包括NIH支持在内的合作互动的实质性证据。教师的研究兴趣包括三个广泛的研究领域：1)病原体诱导的炎症；2)慢性非传染性炎性疾病；3)治疗方法和预防策略。BU-TPID培训学院目前都是美国国立卫生研究院的资助对象，由10个美国国立卫生研究院资助，作为一个群体，他们有丰富的培训历史。作为一个整体，这个群体在各自的领域享有国内和国际的认可。作为培训补助金的一部分，核心培训教员还将参与指导其他初级教员。BU-TPID的教师代表了广泛的部门隶属关系，包括波士顿大学医学院的医学系、微生物系、病理学、生理学和生物物理系、波士顿大学公共卫生学院的环境卫生系、牙科医学院的口腔生物学和口腔医学系以及波士顿大学工程学院的生物医学工程系。

DESCRIPTION (provided by applicant): The proposed training program will provide predoctoral and postdoctoral trainees with a solid academic background in immunology with emphasis on multi disciplinary approaches to study common mechanisms of inflammation. Training will include relevant course work, regularly scheduled seminars and journal clubs, and rigorous laboratory training with the goal of preparing our trainees for careers in research related to the goals of this program. Boston University has an outstanding group of faculty with long standing interests in inflammatory disorders who are members of the Boston University Training Program in Inflammatory Disorders (BU-TPID). In addition, recent recruitment efforts have resulted in the formation of a critical mass of established investigators and accordingly this application proposes to establish an integrated training program for predoctoral students and postdoctoral fellows in inflammatory disorders. In addition to their common research interests, many of these faculties already have substantial evidence for collaborative interactions including NIH support. Faculty research interests encompass three broad research areas including 1) Pathogen induced inflammation; 2) Chronic non-communicable inflammatory disorders; and 3) Therapeutics and preventative strategies. The BU-TPID Training Faculty all are current NIH grant recipients with funding from 10 NIH Institutes, and who, as a group have had substantial training history. As a whole this group enjoys national and international recognition in their respective fields. As part of this training grant the Core training faculty will also be involved in mentoring additional junior faculty members. The BU-TPID faculty represent a broad range of departmental affiliations, including the Departments of Medicine, Microbiology, Pathology, Physiology and Biophysics at the Boston University School of Medicine, the Department of Environmental Health at the Boston University School of Public Health, the Department of Oral Biology and Peridontology at the School of Dental Medicine and the Department of Biomedical Engineering at the Boston University College of Engineering. The major goals of the program will be to 1) Recruit and enroll students of the highest quality, including underrepresented minorities; 2) Provide these trainees with a multidisciplinary background in inflammatory disorders coupled with intensive laboratory training in a particular research topic; 3) To teach the trainees critical thinking skills and how to ask relevant and feasible research questions; 4) To instill these trainees with a sense of ethical behavior; 5) To help develop effective written and oral communication skills among the trainees; 6) To facilitate collaborative interactions among both trainees and faculty of the training program and 7) To mentor Junior faculty members in pre and post doctoral training. PUBLIC HEALTH RELEVANCE: The rationale for establishing the BU-TPID was based on the common research interests of a number of investigators at Boston University, the recognition of the need to establish an integrated program in inflammatory disorders, and to train students and fellows in common mechanisms of inflammation with particular emphasis on clinical and translational science. A hallmark of the BU-TPID is its interschool, interdepartmental and interdisciplinary nature.