K12 In Diabetes (KIDS)

描述(由申请人提供)：加州大学旧金山分校(UCSF)被誉为世界上最强大的健康科学校园之一，部分原因是在生物医学(基于实验室)、转换和临床研究方面的出色培训计划。这个应用程序设想了一个儿科内分泌学家糖尿病研究的职业发展计划，称为KILDS(糖尿病中的K12)。我们申请的首要目标是为致力于1型糖尿病(T1 DM)研究的儿科内分泌学初级教员提供杰出、专注、有结构、有指导和培育的职业发展、培训和支持。我们建议的计划建立在儿科内分泌科和我们备受推崇的糖尿病中心的成功和经验的基础上，前者拥有长期的T32奖学金计划，后者拥有糖尿病教育和研究中心(DERC)。这些整合良好的中心拥有大量的基础设施和资源，将扩大我们的学者在独立的学术生涯中取得成功的机会的广度和深度，并为T1 DM领域做出重大贡献。儿童学者将由一个多学科咨询委员会通过当地招聘和全国搜索来挑选。根据研究重点，学者将被整合到一个强大的，预先存在的临床和翻译科学研究所(CTSI)和相关的K12计划，或生物医学科学方面的类似计划。他们将根据自己以前的经验和职业目标，接受生物医学、转化或临床研究方面的培训。学者们将在指导团队的仔细监督下制定个性化的职业道路，从相关研究领域的教学培训以及他们具体研究项目的开发和执行中建立基础。学者们将有机会接触到一群在T1 DM研究的各个方面都很有成就的研究人员，他们致力于充当学者导师。聚集在一起的教师导师在加州大学旧金山分校糖尿病社区(以及其他社区)形成互动、协作网络的历史，这有助于儿童学者多学科团队的发展。儿童计划的具体目标是：1.在学术生涯早期招募一批优秀和多样化的学者(包括种族和科学方面的)，并在他们成为T1 DM研究领域强大的独立研究员后的头几年为他们提供支持。2.与其他大学资源合作，提供杰出的、多学科的、生物医学、翻译和/或临床研究培训，如CTSI和相关的临床和翻译科学培训计划(CTST)，因为学者们正在追求T1 DM的学术生涯。3.为每一位学者提供学术“孵化器”，提供丰富和持久的指导经验，并通过以下方式促进科学事业发展：a)将学者与来自不同学科的经验丰富的指导团队配对；b)确保学者融入加州大学旧金山分校的生物医学、临床和翻译研究计划；c)通过提供对未来成功至关重要的相关核心学科的综合学术培训，教育学者；d)通过“无缝”访问科学和行政基础设施和核心方法专家，支持学者研究；e)确保学者接受进行研究的道德培训和研究合规。4.在加州大学旧金山分校和全国各地培养儿科糖尿病和T1DM研究的下一代导师和领导者。

DESCRIPTION (provided by applicant): The University of California, San Francisco (UCSF) is renowned as one of the strongest health sciences campuses in the world, in part due to the outstanding training programs in biomedical (laboratory-based), translational, and clinical research. This application envisions a Career Development Program in Diabetes Research for Pediatric Endocrinologists, called KIDs (K12 In Diabetes). The overriding goal of our application is to provide outstanding, focused, structured, mentored, and nurturing career development, training, and support for junior faculty in Pediatric Endocrinology who are committed to pursuing academic careers in type 1 diabetes mellitus (T1DM) research. Our proposed program builds on the successes and experiences of our Pediatric Endocrinology Division, with a longstanding T32 fellowship program, and our highly regarded Diabetes Center, with a Diabetes Education and Research Center (DERC). These well integrated centers, with substantial infrastructure and resources, will enhance the breadth and depth of opportunities for our Scholars to be successful in their independent academic career paths and to contribute significantly to the field of T1DM. KIDs Scholars will be selected by a multi-disciplinary Advisory Board through local recruitment as well as a national search. Depending on research focus, the Scholars will be integrated into either a robust, pre-existing Clinical and Translational Science Institute (CTSI) with an associated K12 program, or comparable programs in the biomedical sciences. They will pursue training in biomedical, translational or clinical research, depending on their prior experiences and career goals. The Scholars will develop an individualized career path with careful oversight from a Mentoring Team, establishing a foundation from didactic training in relevant research areas, and development and execution of their specific research projects. The Scholars will have access to a diverse group of highly accomplished investigators in various aspects of T1DM research, who are committed to serving as Scholar Mentors. The assembled Faculty Mentors have a history of forming interactive, collaborative networks in the UCSF diabetes community (and beyond), which lends itself to the development of multi-disciplinary teams for the KIDs Scholars. The specific aims of the KIDs Program are: 1. To recruit a superb and diverse (both ethnically and scientifically) group of Scholars early in their academic careers and to support them in their first few years beyond fellowship as they become strong independent investigatorsin T1DM research. 2. To provide outstanding, multidisciplinary, biomedical, translational, and/or clinical research training in partnership with other university resources, such as theCTSI and associated Clinical and Translational Science Training Program (CTST), as Scholars pursue academic careers in T1DM. 3. To provide an academic "incubator" for each Scholar that provides a rich and lasting mentored experience and fosters scientific career development through: a) pairing Scholars with experienced Mentoring Teams from diverse disciplines; b) assuring Scholar integration into biomedical, clinical and translational research programs at UCSF; c) educating Scholars by providing integrated scholastic training in relevant core disciplines critical to future success; d) supporting Scholar research by providing "seamless" accessibility to scientific and administrative infrastructure and core methodology experts; e) ensuring that Scholars are trained in the ethics of conducting research and research compliance. 4. To develop the next generation of mentors and leaders in Pediatric Diabetes and T1DMresearch at UCSF and around the country.