BMI Bioinformatics Training Grant

描述（申请人提供）：生物信息学研究生组寻求第二次更新其生物信息学和计算生物学培训计划。该计划的重点是培养年轻科学家，他们可以在计算和生物学之间的界面研究中担任领导者。重点领域包括这些领域以及复杂的生物系统和数量遗传学和基因组学。课程作业、丰富活动和研究的培训计划反映了加州大学旧金山分校的基本合作文化。因此，该项目的正式和非正式特点都旨在将来自不同学科的学生聚集在一起，培养他们以团队为基础解决问题的能力。虽然重点是计算研究，但所有学生都必须进行实验轮换，并在许多其他方面的训练中大量接触实验生物学。因此，我们的毕业生了解他们的实验数据的来源以及如何操作它，并准备在需要理解“湿”和“干”科学文化的多学科团队中进行互动。我们招募了一群具有计算和定量背景的多元化和有才华的学生，并训练他们在跨越分子到表型的尺度上解决生物学中的挑战性问题。因为加州大学旧金山分校是一所健康科学校园，我们的许多学生都在做与人类健康和疾病相关的研究。我们节目的特色是：

DESCRIPTION (provided by applicant): Graduate Group in Bioinformatics seeks a second renewal of its training program in Bioinformatics and Computational Biology. The program focuses on training young scientists who can serve as leaders in research at the interface between computation and biology. Emphasis areas include these fields as well as Complex Biological Systems and Quantitative Genetics and Genomics. The training plan for coursework, enrichment activities, and research reflects the fundamentally collaborative culture at UCSF. Thus, both the formal and informal features of the program have been designed to bring together students from different disciplines and train them for team-based problem solving. Although the focus is on computational research, all students must perform an experimental rotation and are heavily exposed to experimental biology in many other aspects of their training. As a result, our graduates understand the sources of their experimental data as well as how to manipulate it and are prepared to interact in multidisciplinary teams that require an understanding of both "wet" and "dry" scientific cultures. We recruit a diverse and talented group of students with computational and quantitative backgrounds and train them to tackle challenging problems in biology at scales that span the molecular to the phenotypic. Because UCSF is a health sciences campuses, many of our students do research explicitly associated with human health and disease. The special features of our program are: Collaborative and inter-disciplinary research. Training faculty are heavily involved in collaborative research, both within and outside of UCSF. Many of their labs (and trainees) are involved in Consortia or Centers created to address problems that cannot be solved from a single viewpoint but require contributions from many disciplines. Student publications reflect this culture as do student initiated journal clubs and interest groups bringing together students from multiple disciplines for "Research in Progress" talks. An innovative curriculum and special training features. Our core values of collaboration and inter- disciplinary research involve first-year students in team-based and hands-on learning. These special features of First Year training begins with a "Bootcamp" experience taught by senior students and then proceeds to a major integrative biological "Systems" course in the fall quarter featuring student teams chosen to span their different backgrounds. A Core curriculum follows in the winter to teach relevant fundamentals. The spring quarter has been refactored to provide a menu of in-depth "mini-courses" held in a small group format for substantive interactions with faculty with deep research involvement in each area. Significant training in communication and preparation for diverse careers. Students get intensive training in oral and written communication taught in formal courses designed in part by professional staff. Many other venues teach these skills more informally. Students also are given many opportunities to participate in internships, career preparation workshops, and medical education.