BMI Bioinformatics Training Grant

描述(由申请者提供)：生物信息学研究生小组寻求第二次更新其生物信息学和计算生物学的培训计划。该计划的重点是培养年轻的科学家，他们可以在计算和生物学之间的研究中担任领导者。重点领域包括这些领域以及复杂生物系统和数量遗传学和基因组学。课程、充实活动和研究的培训计划反映了加州大学旧金山分校的基本合作文化。因此，该项目的正式和非正式功能都被设计为将来自不同学科的学生聚集在一起，并培训他们进行基于团队的问题解决。虽然重点是计算研究，但所有学生都必须进行实验轮换，并在培训的许多其他方面大量接触实验生物学。因此，我们的毕业生了解他们实验数据的来源以及如何处理这些数据，并准备好在需要了解“湿”和“干”科学文化的多学科团队中进行互动。我们招募了一群具有计算和量化背景的多样化和有才华的学生，并培训他们在从分子到表型的范围内解决生物学中具有挑战性的问题。由于加州大学旧金山分校是一个健康科学校园，我们的许多学生从事明确与人类健康和疾病相关的研究。我们节目的特点是： 协作性和跨学科研究。培训人员积极参与加州大学旧金山分校内外的合作研究。他们的许多实验室(和受训人员)参与了为解决不能从单一角度解决但需要多个学科贡献的问题而创建的联盟或中心。学生出版物反映了这一点 学生发起的期刊俱乐部和兴趣小组也是如此，他们将来自多个学科的学生聚集在一起，进行“正在进行的研究”演讲。 具有创新的课程设置和专项培训特色。我们的合作和跨学科研究的核心价值观是让一年级学生参与基于团队和实践的学习。第一年培训的这些特殊功能从高年级学生教授的“训练营”体验开始，然后在秋季继续进行一个主要的综合生物学“系统”课程，学生团队被挑选出来，跨越不同的背景。核心课程将在冬季开设，教授相关的基础知识。春季班已进行了重组，以小组形式提供了一系列深入的“迷你课程”，以便与在每个领域都有深入研究参与的教职员工进行实质性互动。 在沟通和为不同职业做准备方面进行了重要的培训。学生们在专业人员设计的正式课程中接受口头和书面交流的强化培训。许多其他场所更多地非正式地教授这些技能。学生还有很多机会参加实习、职业准备研讨会和医学教育。

DESCRIPTION (provided by applicant): Graduate Group in Bioinformatics seeks a second renewal of its training program in Bioinformatics and Computational Biology. The program focuses on training young scientists who can serve as leaders in research at the interface between computation and biology. Emphasis areas include these fields as well as Complex Biological Systems and Quantitative Genetics and Genomics. The training plan for coursework, enrichment activities, and research reflects the fundamentally collaborative culture at UCSF. Thus, both the formal and informal features of the program have been designed to bring together students from different disciplines and train them for team-based problem solving. Although the focus is on computational research, all students must perform an experimental rotation and are heavily exposed to experimental biology in many other aspects of their training. As a result, our graduates understand the sources of their experimental data as well as how to manipulate it and are prepared to interact in multidisciplinary teams that require an understanding of both "wet" and "dry" scientific cultures. We recruit a diverse and talented group of students with computational and quantitative backgrounds and train them to tackle challenging problems in biology at scales that span the molecular to the phenotypic. Because UCSF is a health sciences campuses, many of our students do research explicitly associated with human health and disease. The special features of our program are: Collaborative and inter-disciplinary research. Training faculty are heavily involved in collaborative research, both within and outside of UCSF. Many of their labs (and trainees) are involved in Consortia or Centers created to address problems that cannot be solved from a single viewpoint but require contributions from many disciplines. Student publications reflect this culture as do student initiated journal clubs and interest groups bringing together students from multiple disciplines for "Research in Progress" talks. An innovative curriculum and special training features. Our core values of collaboration and inter- disciplinary research involve first-year students in team-based and hands-on learning. These special features of First Year training begins with a "Bootcamp" experience taught by senior students and then proceeds to a major integrative biological "Systems" course in the fall quarter featuring student teams chosen to span their different backgrounds. A Core curriculum follows in the winter to teach relevant fundamentals. The spring quarter has been refactored to provide a menu of in-depth "mini-courses" held in a small group format for substantive interactions with faculty with deep research involvement in each area. Significant training in communication and preparation for diverse careers. Students get intensive training in oral and written communication taught in formal courses designed in part by professional staff. Many other venues teach these skills more informally. Students also are given many opportunities to participate in internships, career preparation workshops, and medical education.