Signal Transduction Mechanism of Osteoclast Differentiation

破骨细胞分化的信号转导机制

• 批准号: 7910474
• 负责人: NANDINI GHOSH-CHOUDHURY
• 金额: --
• 依托单位: SOUTH TEXAS VETERANS HEALTH CARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7910474
• 关键词: Adult; Aging; American; Binding; Biological Assay; Bone Diseases; Bone Morphogenetic Proteins; Bone Pain; Bone Regeneration; Bone Resorption; Bone neoplasms; Bone remodeling; Calvaria; Cell Surface Receptors; Cells; Childhood; Coculture Techniques; Complex; Connective Tissue; DNA; Data; Disease; Drug Design; Elderly; Electrophoretic Mobility Shift Assay; Elements; Engineering; Equilibrium; Fracture; Future; Gene Expression; Gene Expression Regulation; Genes; Health; Hip Fractures; Homeostasis; Hydroxyapatites; Immunoblotting; Immunohistochemistry; In Situ Hybridization; In Vitro; Lead; Ligands; Macrophage Colony-Stimulating Factor; Macrophage Colony-Stimulating Factor Receptor; Malignant Bone Neoplasm; Measures; Mediating; MicroRNAs; Molecular; Mus; Neoplasm Metastasis; Nuclear; Osteitis Deformans; Osteoblasts; Osteoclasts; Osteocytes; Osteogenesis; Osteoporosis; Pathology; Periodontosis; Pharmaceutical Preparations; Population; Post-Transcriptional Regulation; Postmenopausal Osteoporosis; Process; Publishing; Rattus; Receptor Gene; Regulation; Reporting; Rheumatoid Arthritis; Role; Signal Pathway; Signal Transduction; Site-Directed Mutagenesis; Skeleton; Spleen; Stromal Cells; Surface; Techniques; Testing; Therapeutic; Therapeutic Intervention; Time; Transcriptional Regulation; Transfection; Tumor necrosis factor receptor 11b; Veterans; War; Work; activating transcription factor; autoimmune arthritis; base; bone; bone loss; bone mass; bone morphogenetic protein 2; bone resorbing activity; bone turnover; calcium phosphate; chromatin immunoprecipitation; fetus cell; improved; interest; mRNA Expression; macrophage; men; monocyte; novel; nuclear factors of activated T-cells; osteoblast differentiation; osteoclastogenesis; paracrine; prevent; progenitor; promoter; public health relevance; receptor; receptor expression; research study; response; transcription factor; young adult