Targeting IKK beta and aurora kinases in melanoma

靶向黑色素瘤中的 IKK β 和极光激酶

• 批准号: 7912888
• 负责人: Ann Richmond
• 金额: --
• 依托单位: VETERANS HEALTH ADMINISTRATION
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7912888
• 关键词: Affect; Age; Aneuploidy; Apoptosis; Auras; Cell Death; Cell Division Process; Cell Nucleus; Cell Proliferation; Cells; Cessation of life; Chemical Exposure; Chromosomes; Clinical Trials; Clinical Trials Design; Data; Development; Dysplastic Nevus; Epidemic; Event; Exhibits; Future; Gene Expression; Gene Expression Microarray Analysis; Gene Expression Profile; Gene Targeting; Genetic Transcription; Genomic Instability; Goals; Growth; Growth Factor; Growth Inhibitors; Host Defense; Human; In Vitro; Individual; Inflammation Mediators; Lead; Learning; Lesion; Melanoma Cell; Metastatic Melanoma; Microarray Analysis; Mitosis; Modeling; Molecular Profiling; Mus; Mutation; NF-kappa B; Nevus; Normal Cell; Oncogenes; Oncogenic; Pathway interactions; Patients; Pattern; Pharmaceutical Preparations; Phase; Phosphotransferases; Population; Production; Reporting; Signal Transduction Pathway; Sun Exposure; System; Therapeutic; Tissue Microarray; Tumor Suppressor Proteins; Ubiquitination; Veterans; Xenograft Model; Xenograft procedure; aurora kinase; aurora-A kinase; cancer cell; cancer type; cell growth; chemokine; cytokine; design; experience; improved; inhibitor/antagonist; insight; kinase inhibitor; melanocyte; melanoma; men; older men; older women; p65; preclinical study; public health relevance; response; segregation; transcription factor; tumor; tumor growth; tumor progression