Microtubule dynamics and age-related aneuploidy in mammalian oocytes

哺乳动物卵母细胞的微管动力学和年龄相关的非整倍性

• 批准号: 321378
• 负责人: Fitzharris Greg
• 金额: $ 43.89万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-03-01 至 2020-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=321378&lang=en
• 关键词: Aneuploidy; Chromosome Segregation; Infertility; Motor Proteins; Oocyte; Spindle

At fertilisation a new individual is created by the fusion of the sperm and the egg, each of which contributes half of the genetic material (chromosomes) for the offspring. However, for reasons that are very poorly understood, the development of the egg i

受精时，精子和卵子融合产生一个新个体，每个个体都为后代贡献一半的遗传物质（染色体）。然而，由于人们知之甚少的原因，卵子的发育