HTS for Identifying Allosteric Modulators of TRPV1 receptor
HTS for Identifying Allosteric Modulators of TRPV1 receptor
批准号:
9205731
负责人:
Noel Southall
金额:
$5.7万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
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英文摘要
During this period, the NCGC has fostered and maintained over 180 active collaborations with both NIH and extramural investigators, facilitating drug discovery efforts across the entire spectrum of human disease. These efforts have led to over 100 high-throughput screens and nearly 60 medicinal chemistry campaigns, providing our collaborators and the general research community a wealth of publications and promising small molecule leads. In addition, the NCGC has undertaken a number of informatic challenges to make better use of existing drug and disease target information and provide the general public with easily accessible resources, further catalyzing the development of new therapies for human disease.
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会议论文
Identification of substances that change alternative pre-mRNA splicing of the serotonin 2C receptor
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批准号:9205722
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Inhibitors of Cell Surface uPA Generation
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批准号:9205727
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Malaria Phosphatase Inhibitors Identified as a Potential New Malaria Treatment
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批准号:9205723
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Development of small molecule agonists of the parathyroid hormone receptor type-1 (PTHR1) as potential new therapeutics for the treatment of osteoporosis
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批准号:9550585
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项目类别:
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资助金额:$13.57万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Identification of small molecule RXFP3 ligands
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批准号:10011441
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项目类别:
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资助金额:$4.76万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Development of small molecule agonists of the parathyroid hormone receptor type-1 (PTHR1) as potential new therapeutics for the treatment of osteoporosis
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批准号:10006274
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项目类别:
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资助金额:$25.03万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Development of small molecule agonists of the parathyroid hormone receptor type-1 (PTHR1) as potential new therapeutics for the treatment of osteoporosis
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批准号:9205737
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Noel Southall
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依托单位:
GInAS - Global Ingredient Archival System
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批准号:9205614
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项目类别:
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资助金额:$75.0万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Small molecule inhibitors of mitochondrial division or activators of mitochondrial fusion
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批准号:9205728
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Specific Modulators of the Novel Potassium Channel KCNH2 3.1
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批准号:9205797
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项目类别:
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资助金额:$11.4万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Inxight Informatics System - Repository of Therapeutic Hypotheses
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批准号:10262720
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项目类别:
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资助金额:$298.65万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Modulators of RPS14 with broad antiviral activity
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批准号:10255320
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项目类别:
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资助金额:$11.24万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Quantitative High-Throughput Screen for Inhibitors and Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease
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批准号:9205724
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Quantitative High Throughput Screen to Identify Novel Antivirals against Hepatitis C Virus in a Cell-Based Infection Assay
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批准号:9359878
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项目类别:
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资助金额:$12.2万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Development of small molecule agonists of the parathyroid hormone receptor type-1 (PTHR1) as potential new therapeutics for the treatment of osteoporosis
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批准号:9359879
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项目类别:
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资助金额:$12.2万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Screening for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias
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批准号:9205799
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项目类别:
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资助金额:$11.4万
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财政年份:--
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负责人:Noel Southall
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依托单位:
High-Throughput Screening for Compounds Blocking Interaction Between CBF-beta-SMMHC and RUNX1 for the treatment of Acute Myeloid Leukemia
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批准号:9205798
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项目类别:
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资助金额:$11.4万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Screening for Inhibitors of MLL Translocation Proteins in Leukemia
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批准号:9205729
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项目类别:
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资助金额:$5.7万
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财政年份:--
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负责人:Noel Southall
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依托单位:
NCATS Biomedical Data Translator
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批准号:10269699
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项目类别:
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资助金额:$60.0万
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财政年份:--
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负责人:Noel Southall
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依托单位:
Identification of novel compounds that inhibit human CMV replication
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批准号:9359876
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项目类别:
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资助金额:$12.2万
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财政年份:--
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负责人:Noel Southall
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依托单位:
海外基金