Research Career Development Core

项目摘要（见说明）：RCDC的首要使命是培养未来的领导者在老龄化研究，集中在加州大学洛杉矶分校的主题领域，预防疾病和残疾在弱势群体：一个转化的方法。RCDC将促进未来研究领导者的发展，他们解决这一主题，特别是能够将老年人的健康，疾病，独立性和残疾的临床见解与基础科学（包括老年学）的进步知识相结合的领导者，以制定更好的干预措施来保持健康和独立性。该RCDC的目标是1）确定初级教师谁有最大的潜力，在老龄化研究的未来领导者接受三年的职业发展奖（CDA），专注于我们的OAIC主题; 2）促进研究培训和这些初级科学家的职业生涯; 3）为CDA获奖者提供一个支持性的环境，最大限度地提高成功的培训，研究进展和最终的职业成功的可能性; 4）包括与每个受训者需求相关的转化科学原理和方法的培训; 5）作为加州大学洛杉矶分校初级教师与衰老相关的研究导师资源。为了实现这些目标，加州大学洛杉矶分校RCDC还将对少数民族CDA候选人进行宣传，寻找经过临床培训的候选人，并关注少数民族人口在研究中的代表性的重要性。第一年的4个候选CDA正在进行与UCLA主题相关的研究。Jordan Lake是一位传染病专家，他正在研究慢性炎症加速HIV感染者衰老过程的机制。Judith卡罗尔博士是一位健康心理学家和心理神经免疫学家，其工作重点是使用睡眠作为模型来确定社会，情感，环境和行为因素影响年龄相关疾病，免疫衰老和加速衰老的脆弱性的生物机制。李詹宁斯，医学博士，是一名老年病学家，他正在研究老年人艾滋病毒感染者的医疗保健需求，目的是提高老年人艾滋病毒感染者的医疗保健质量，获得和提供服务。Gerardo Moreno博士是一名家庭医生，他正在研究患有慢性病的弱势老年人的适当药物管理和干预措施，包括决策支持和临床药剂师咨询，以改善初级保健环境中的药物管理。

PROJECT SUMMARY (See instructions): The overarching mission of the RCDC is to develop future leaders in aging research, focused in the area of UCLA's theme, Preventing Disease and Disability in Vulnerable Populations: a Translational Approach. The RCDC will promote the development of future research leaders who address this theme, particularly leaders who can integrate clinical insights regarding health, disease, independence, and disability in older adults with knowledge of advances in the basic sciences, including gerontology, to develop better interventions to maintain health and independence. The goals of the RCDC are to 1) identify junior faculty who have the greatest potential as future leaders in aging research to receive three year career development awards (CDAs), focused on our OAIC theme; 2) foster the research training and careers of these junior scientists; 3) provide a supportive environment for CDA awardees that maximizes the likelihood of successful training, research progress and ultimate career success; 4) Include training in translational science principles and methods relevant to each trainee's needs; and 5) serve as a resource in aging-related research mentorship for UCLA junior faculty. In meeting these goals, the UCLA RCDC will also conduct outreach to minority CDA candidates, seek out candidates who have been clinically trained, and be attentive to the importance of minority populations' representation in research. The 4 candidate CDAs for Year 1 are conducting research related to UCLA's theme. Jordan Lake, MD, is an infectious disease specialist who is examining mechanisms by which chronic inflammation accelerates aging processes in HIV-infected persons. Judith Carroll, PhD, is a health psychologist and psychoneuroimmunologist whose work focuses on using sleep as a model to identify the biological mechanisms through which social, emotional, environmental and behavioral factors influence vulnerability for age-related disease, immunosenescence, and accelerated aging. Lee Jennings, MD, is a geriatrician who is examining the health care needs of older adults with HIV with the aims of improving the quality, access to and delivery of care to older persons with HIV. Gerardo Moreno, MD, is a family physician who is examining appropriate medication management among vulnerable older adults with chronic conditions and interventions including decision support, and clinical pharmacist consultations to improve medication management in primary care settings.