CAP-Assessment Core Boston

CAP-评估核心波士顿

• 批准号: 8827165
• 负责人: BRETT T LITZ
• 金额: --
• 依托单位: VA BOSTON HEALTH CARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8827165
• 关键词: Acute; Address; Alcohol or Other Drugs use; Behavioral; Biological; Biological Markers; Boston; Characteristics; Chronic; Clinical Trials; Cognitive; Common Data Element; Conduct Clinical Trials; Data; Data Set; Detection; Development; Diagnosis; Diagnostic; Dictionary; Ensure; Environmental Exposure; Epidemiologic Studies; Epidemiology; Etiology; Evaluation; Exposure to; Funding; Future; Genetic; Genomics; Goals; Headache; Individual Differences; Institute of Medicine (U.S.); Institutes; Institution; Interest Group; International; Interview; Life Cycle Stages; Measurement; Measures; Medical; Medical center; Mental Depression; Mental Health; Military Personnel; Modeling; NIH Program Announcements; Needs Assessment; Neurobiology; Outcome; Pain; Patients; Personal Satisfaction; Plant Roots; Population; Post-Traumatic Stress Disorders; Prevention; Prevention strategy; Preventive; Procedures; Property; Proteomics; Psychometrics; Publishing; Randomized Clinical Trials; Rehabilitation therapy; Reporting; Research; Research Infrastructure; Research Personnel; Risk; Services; Shapes; Site; Sleep disturbances; South Carolina; Stress; Suicide; Supervision; Systems Biology; Time; Training; Trauma; Treatment outcome; United States National Institutes of Health; Universities; Veterans; War; Work; adjudicate; base; behavioral health; combat; effective intervention; experience; improved; instrumentation; member; multidisciplinary; neuroimaging; novel; outcome forecast; physical conditioning; post-traumatic stress; preclinical study; prevent; prognostic; psychologic; resilience; sound; success; treatment response

The Assessment Core has four main objectives that support proposed and future clinical trials and epidemiological studies: (1) to create uniformity of instrumentation and measurement and to employ state-of- the-art measures with sound psychometric properties; (2) to ensure measurement of outcome and predictor variables that are relevant and sensitive to the active duty military ethos and culture as well as Veterans' experiences; (3) to train and to provide oversight and supervision of Independent Evaluators (IEs), to adjudicate diagnostic decisions for clinical trials when necessary, to conduct inter-rater reliability evaluations of taped PTSD interviews, and to shape IEs over time to obviate drift; and (4) to work with the Data and Epidemiological Cores to create a data dictionary and to manage and leverage the omnibus multi-study dataset. Our team has specialized expertise in the assessment of war-trauma (Litz, 2007; Litz & Schlenger, 2009; Steenkamp et al., 2010; Stein et al., 2012) and has extensive experience measuring risk and resilience in the military over the life-course (Baker et al., 2012; Dickstein et al., 2010). The infrastructure created under STRONG STAR is well-equipped to effectively oversee the measurement and assessment needs for STRONG STAR-CAP. To date, we have selected outcome and predictor variables that are state-of-the-art and that provide content coverage across multiple domains while respecting Service Members' and Veterans time-and- effort constraints. We were especially mindful of the latter and chose briefer options whenever possible. Ronald Acierno at the Charleston VA Medical Center/Medical University South Carolina has organized an informal research Consortium consisting of approximately 10 non-NCPTSD investigators located at VAs throughout the US (see Table 5) who are committed to partnering with the Assessment Core and the STRONG STAR-CAP. All of the investigators have current VA, DoD, or NIH funding to support their PTSD research. A primary interest of this group is to help ensure that a set of Common Data Elements (Kaloupek et al., 2010) are collected across all DoD and VA STRONG STAR-CAP-affiliated studies (e.g., common psychological construct domains, biomarkers, etc.). They have titled their effort the Coalition of VA/DoD PTSD CAP Study Site Partners for Common Data Elements.

评估核心有四个主要目标，支持拟议和未来的临床试验， 流行病学研究：（1）建立统一的仪器和测量，并采用国家的， 具有良好心理测量特性的最先进的测量方法;（2）确保测量结果和预测因素 变量是相关的和敏感的现役军事精神和文化，以及退伍军人的 （3）培训和监督独立评估员， 必要时裁定临床试验的诊断决策，以进行评估者间可靠性评估 录音的PTSD采访，并随着时间的推移塑造IE，以适应漂移;（4）与数据和 流行病学核心，用于创建数据字典，并管理和利用综合多研究数据集。 我们的团队在战争创伤评估方面具有专业知识（Litz，2007; Litz & Schlenger，2009; Steenkamp等人，2010; Stein等人，2012年），并在衡量风险和弹性方面拥有丰富的经验， 生命过程中的军事（Baker等人，2012; Dickstein等人，2010年）。基础设施建设在 STRONG星星配备齐全，可有效监督STRONG的测量和评估需求 星帽迄今为止，我们已经选择了最先进的结果和预测变量，并且 提供跨多个领域的内容覆盖，同时尊重服务成员和退伍军人的时间和 努力的限制。我们特别注意后者，并尽可能选择较简短的选项。罗纳德 查尔斯顿退伍军人医疗中心/南卡罗来纳州医科大学的Acierno组织了一次非正式的 研究联盟，由大约10名非NCPTSD研究者组成，位于整个 美国（见表5），致力于与评估核心和STRONG STAR-CAP合作。所有 的研究人员目前有VA，DoD或NIH的资金支持他们的PTSD研究。主要兴趣 是帮助确保一组公共数据元素（Kaloupek等人，2010年），收集 所有DoD和VA STRONG STAR-CAP附属研究（例如，共同的心理建构领域， 生物标志物等）。他们将他们的努力命名为VA/DoD PTSD CAP研究网站合作伙伴联盟， 通用数据元素。