Research Training Program in Surgical Oncology

肿瘤外科研究培训计划

• 批准号: 8685750
• 负责人: Kirby I. Bland
• 金额: $ 31.78万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8685750
• 关键词: Research Training; Surgical Oncology; Training Programs

DESCRIPTION (provided by applicant): This competitive renewal was originally funded in 2002, and is now completing the fourth year of its second five-year cycle (10th year). This T32 builds upon established clinical and scientific strengths in various oncologic disciplines of the Departments of Surgery and Obstetrics/Gynecology. The partnership of both Departments with UAB Comprehensive Cancer Center provides an integrated infrastructure of collaborative bench science that spans fundamental molecular discovery to move scientific inquiry from bench-to-bedside for applied clinical and translational research. This training environment enhances the intra-collaborative, seamless trans-departmental initiatives available in Tumor Biology and Immunology, Human Genetics, Autoimmunity and Inflammation, Translational Clinical and Outcomes Research. The strategic goals of the research plan have special emphasis on the training of nascent, promising young Surgical-Scientists in their early post-doctoral years and who are in ACGME-approved training programs in Surgery or Gynecologic Oncology. Thus, this T-32 program coordinates the mentorship of promising post- doctoral ACGME resident-candidates who will aspire to academic faculty positions and will strengthen UAB's exceptional mentoring environment. This T-32 grant represents a mechanism for faculty collaboration and synergistic scientific interests among its four SPORE programs at UAB. Programmatically, an effective interdisciplinary research experience is implemented by the obligatory incorporation of the required teaching via mentors and the required course work for individual research plans. Course work in statistics and ethical conduct of research is augmented in this competitive renewal with formal instruction provided by the Center for Clinical and Translational Science (CCTS) and the Office of Post-Doctoral Education in grantsmanship, manuscript writing, and translational research. Over the past five years, 22 ACGME resident-trainees in Surgery and Gynecologic Oncology were supported by this T-32 mechanism. Because post-graduate surgical training approaches 7-10 years, and T-32 Trainees conduct research in the early stages of their career, a significant number of trainees still have >5 years of surgical training remaining prior to academic appointment. Therefore, we are just beginning to see the academic success of our program after 10 years of continuous funding. In the past 10 years, there have been 36 trainees that have completed their T-32 training with 70 % of these residents continuing in academic biomedical research and practice / training. Moreover, in the past five years, this T-32 has been gender-balanced and has included 17% under-represented minorities. This T32 has, over the past ten years, provided continual strong commitment to trainees with oversight and encouragement of reciprocal commitment to careers in investigation and academia. This is reflected by those who have completed training with academic faculty positions in other Schools of Medicine within Departments of Surgery, its oncology disciplines, and Obstetrics/Gynecology. Continued funding is therefore requested annually for 6 post-doctoral resident-trainees.

描述（由申请人提供）：这项竞争性更新最初于2002年获得资助，目前已完成第二个五年周期（第10年）的第四年。这个T32建立在外科和产科/妇科的各种肿瘤学科的临床和科学优势之上。这两个部门与UAB综合癌症中心的合作伙伴关系提供了协作实验科学的综合基础设施，涵盖了基础分子发现，将科学探究从实验台转移到临床应用和转化研究的床边。这种培训环境增强了肿瘤生物学和免疫学、人类遗传学、自身免疫和炎症、转化临床和结果研究等领域的内部协作、无缝跨部门倡议。该研究计划的战略目标特别强调在早期博士后阶段培养新生的、有前途的年轻外科科学家，并在acgme批准的外科或妇科肿瘤学培训项目中学习。因此，这个T-32项目协调了有前途的博士后ACGME常驻候选人的指导，这些候选人将渴望获得学术教职，并将加强UAB卓越的指导环境。这项T-32拨款代表了UAB四个SPORE项目之间教师合作和协同科学利益的机制。在程序上，有效的跨学科研究经验是通过导师的必要教学和个人研究计划的必修课程的强制性结合来实现的。临床和转化科学中心（CCTS）和博士后教育办公室在资助、手稿写作和转化研究方面提供正式指导，在这一竞争激烈的更新中，统计学和研究伦理行为的课程得到了加强。在过去的五年中，22名ACGME外科和妇科肿瘤住院实习医师接受了T-32机制的支持。由于研究生外科训练接近7-10年，而T-32受训者在其职业生涯的早期阶段进行研究，因此相当多的受训者在学术任命之前仍然有50年的外科训练。因此，经过10年的持续资助，我们刚刚开始看到我们的项目在学术上的成功。在过去10年中，有36名实习生完成了T-32培训，其中70%的住院医生继续从事学术生物医学研究和实践/培训。此外，在过去的五年里，这架T-32一直是性别平衡的，其中包括17%的代表性不足的少数民族。在过去的十年里，这个T32一直为学员提供强有力的承诺，监督和鼓励他们在调查和学术领域的相互承诺。这反映在那些在其他医学院外科、肿瘤学科和产科/妇科部门完成学术教职培训的人身上。因此，每年要求继续资助6名博士后住院培训生。