Research Training Program in Surgical Oncology

描述（由申请人提供）：该竞争性更新最初于2002年获得资助，目前正在完成第二个五年周期的第四年（第10年）。该T32建立在外科和妇产科各肿瘤学科的临床和科学优势基础上。这两个部门与UAB综合癌症中心的合作伙伴关系提供了一个合作实验室科学的综合基础设施，涵盖了基础分子发现，将科学研究从实验室转移到临床应用和转化研究。这种培训环境增强了肿瘤生物学和免疫学，人类遗传学，自身免疫和炎症，转化临床和成果研究中的内部协作，无缝跨部门举措。 该研究计划的战略目标特别强调在早期博士后阶段培养新生的，有前途的年轻外科科学家，并且他们正在接受ACGME批准的外科或妇科肿瘤培训计划。因此，这个T-32计划协调有前途的博士后ACGME居民候选人谁将渴望学术教师职位的指导，并将加强UAB的特殊辅导环境。这个T-32补助金代表了UAB四个SPORE项目之间的教师合作和协同科学兴趣的机制。在程序上，有效的跨学科研究经验是通过导师所需的教学和个人研究计划所需的课程工作的强制性结合来实现的。在统计学和研究的道德行为课程工作是在这个竞争性的更新与临床和转化科学中心（CCTS）和博士后教育办公室在granitary，手稿写作和转化研究提供的正式指令增强。在过去的五年中，22 ACGME住院实习生在外科和妇科肿瘤是由这个T-32机制的支持。由于研究生外科培训接近7-10年，而T-32受训者在职业生涯的早期阶段进行研究，因此相当多的受训者在学术任命之前仍然有超过5年的外科培训。因此，经过10年的持续资助，我们才刚刚开始看到我们项目的学术成功。在过去的10年里，有36名学员完成了T-32培训，其中70%的住院医师继续从事学术生物医学研究和实践/培训。此外，在过去五年中，T-32一直是性别平衡的，包括17%的代表性不足的少数民族。在过去的十年中，T32为学员提供了持续的坚定承诺，并监督和鼓励对调查和学术界职业的相互承诺。这反映在那些谁已经完成了在外科，肿瘤学科和妇产科的其他医学院的学术教师职位的培训。因此，每年要求继续为6名博士后实习生提供资金。

DESCRIPTION (provided by applicant): This competitive renewal was originally funded in 2002, and is now completing the fourth year of its second five-year cycle (10th year). This T32 builds upon established clinical and scientific strengths in various oncologic disciplines of the Departments of Surgery and Obstetrics/Gynecology. The partnership of both Departments with UAB Comprehensive Cancer Center provides an integrated infrastructure of collaborative bench science that spans fundamental molecular discovery to move scientific inquiry from bench-to-bedside for applied clinical and translational research. This training environment enhances the intra-collaborative, seamless trans-departmental initiatives available in Tumor Biology and Immunology, Human Genetics, Autoimmunity and Inflammation, Translational Clinical and Outcomes Research. The strategic goals of the research plan have special emphasis on the training of nascent, promising young Surgical-Scientists in their early post-doctoral years and who are in ACGME-approved training programs in Surgery or Gynecologic Oncology. Thus, this T-32 program coordinates the mentorship of promising post- doctoral ACGME resident-candidates who will aspire to academic faculty positions and will strengthen UAB's exceptional mentoring environment. This T-32 grant represents a mechanism for faculty collaboration and synergistic scientific interests among its four SPORE programs at UAB. Programmatically, an effective interdisciplinary research experience is implemented by the obligatory incorporation of the required teaching via mentors and the required course work for individual research plans. Course work in statistics and ethical conduct of research is augmented in this competitive renewal with formal instruction provided by the Center for Clinical and Translational Science (CCTS) and the Office of Post-Doctoral Education in grantsmanship, manuscript writing, and translational research. Over the past five years, 22 ACGME resident-trainees in Surgery and Gynecologic Oncology were supported by this T-32 mechanism. Because post-graduate surgical training approaches 7-10 years, and T-32 Trainees conduct research in the early stages of their career, a significant number of trainees still have >5 years of surgical training remaining prior to academic appointment. Therefore, we are just beginning to see the academic success of our program after 10 years of continuous funding. In the past 10 years, there have been 36 trainees that have completed their T-32 training with 70 % of these residents continuing in academic biomedical research and practice / training. Moreover, in the past five years, this T-32 has been gender-balanced and has included 17% under-represented minorities. This T32 has, over the past ten years, provided continual strong commitment to trainees with oversight and encouragement of reciprocal commitment to careers in investigation and academia. This is reflected by those who have completed training with academic faculty positions in other Schools of Medicine within Departments of Surgery, its oncology disciplines, and Obstetrics/Gynecology. Continued funding is therefore requested annually for 6 post-doctoral resident-trainees.