UTMB Clinical and Translational Science Award

UTMB 临床和转化科学奖

• 批准号: 9085702
• 负责人: MARK R HELLMICH
• 金额: $ 32.66万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2020-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9085702
• 关键词: Academic Training; Address; Award; Basic Science; Behavior Therapy; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Communication; Development; Devices; Diagnostic; Discipline; Disease; Doctor of Philosophy; Educational Curriculum; Enrollment; Entrepreneurship; Ethical Issues; Faculty; Fellowship; Funding; Future; Goals; Health; Human; Human Subject Research; Hybrids; Industry; Intervention; Knowledge; Laboratories; Leadership; Letters; Mediation; Medical Students; Mentors; Methods; Modeling; Pharmaceutical Preparations; Positioning Attribute; Postdoctoral Fellow; Program Evaluation; Recruitment Activity; Research; Research Activity; Research Design; Research Infrastructure; Research Project Grants; Research Training; Resources; Rotation; Schools; Science; Students; Testing; Therapeutic; Training; Training Programs; Training Support; Translational Research; Underrepresented Minority; Work; base; conflict resolution; graduate student; improved; innovation; meetings; multidisciplinary; pre-doctoral; programs; science education; skills; success; tool

ABSTRACT This TL1 Training Core, in support of the UTMB CTSA U54 application, will provide “predoctoral students (3 trainees/year) with a deep orientation to translational science, and postdoctoral fellows (3 scholars/year) with advanced research training aligned with the CTSA's goals of advancing therapeutics (drugs, devices, diagnostics and preventatives), clinical interventions, and behavioral modifications to improve human health.” Existing curricula and training programs at UTMB, as elsewhere, excel at developing discipline-specific knowledge and technical skills, but are less effective at developing the core skills and competencies essential for the effective and efficient practice of team-based translational science; these are: team management, shared leadership, conflict resolution and negotiations, interprofessional communication, entrepreneurship, and the regulatory and ethical issues associated with human subjects research and clinical trials. To address this gap, we will build on our CTSA hub's successful application of a hybrid industry “work team”-academic approach to translational research using a Multidisciplinary Translational Team (MTT) model. We will also use a training model that is based on our successful implementation of a competency-driven curriculum for a new translational PhD program. We will recruit from a sufficiently large pool of trainees in any of our 13 biomedical graduate programs, including a large proportion of underrepresented minorities, which is mirrored by a diverse faculty. Of key importance, the GSBS and the UTMB Provost initiated and fund financial supplements for students recruited as Presidential Scholars to encourage the enrollment of outstanding graduate students. Potential trainees will be advised to pursue laboratory rotations with MTT-based faculty. Once a mentoring team is selected, students and their mentors will apply for training positions (predoctoral fellowship) in the TL1 Training Core. Postdoctoral scholars will be specifically recruited to the program by MTT-based mentors (Program Faculty). Among others, three particularly innovative components of the required curriculum include: 1) the Interprofessional Translational Research Design Course, which includes medical students and PhD students working in teams; 2) the Clinical Encounters Program, which addresses the need for trainees and scholars to be educated in the human health- and disease-related aspects of their research; and 3) dissertation/postdoctoral research projects co-mentored by both scientific and clinical experts. Lastly, our training program's evaluations will use relevant, validated assessment tools such as the Teamwork Competency Test and others. Primary financial resources, space, and staff are committed by UTMB to provide oversight, key core resources, integrative programs and seminars for this Training Core. The Graduate School of Basic Sciences also provides financial and infrastructure support for the Training Core. Lastly, the supporting letter from the UTMB Provost enumerates the current and future commitments to the ITS, which assure the success of this oversight entity for our innovative training program.

抽象的 在支持UTMB CTSA U54应用程序的TL1培训核心将提供“前学生（3个） 受训者/年），对转化科学的深入方向，以及博士后研究员（3个学者/年） 高级研究培训符合CTSA的进步治疗目标（药物，设备， 诊断和预防剂），临床干预措施和行为修改以改善人类健康。” 与其他地方一样 知识和技术技能，但在开发核心技能和能力基本的能力方面的有效性较小 为基于团队的转化科学的有效实践；这些是：团队管理， 共同的领导，解决冲突和谈判，跨专业沟通，企业家精神和 与人类受试者研究和临床试验相关的监管和道德问题。解决这个问题 GAP，我们将基于CTSA枢纽成功地应用混合行业“工作团队” - 学术 使用多学科翻译团队（MTT）模型进行翻译研究的方法。我们还将使用 一个基于我们成功实施能力驱动的课程的培训模型 翻译博士计划。我们将从我们13个生物医学中的任何一个中的任何一个都有足够大的受训者中招募 研究生课程，包括大部分代表性不足的少数民族，这是由潜水员反映的 学院。重要的是，GSB和UTMB教务长启动并资助财务补充 学生被招募为总统学者，以鼓励入学杰出的研究生。 建议潜在的受训人员与基于MTT的教职员工一起购买实验室轮换。曾经是一个心理 选出团队，学生及其导师将申请TL1的培训职位（前奖学金） 训练核心。博士后学者将由MTT的导师专门招募该计划 （课程教师）。除其他外，所需课程的三个特别创新的组成部分包括： 1）跨专业翻译研究设计课程，其中包括医学生和博士学位 在团队中工作的学生； 2）临床遭遇计划，该计划满足了培训的需求 学者将在其研究的人类健康和疾病相关方面接受教育； 3） 学位论文/博士后研究项目由科学和临床专家共同注册。最后，我们的 培训计划的评估将使用相关的，经过验证的评估工具，例如团队合作 能力测试等。 UTMB致力于提供的主要财务资源，空间和员工提供 该培训核心的监督，关键核心资源，集成计划和下水道。研究生院 基本科学还为培训核心提供财务和基础设施支持。最后， UTMB教务长的支持信列举了对ITS的当前和未来承诺， 确保该监督实体在我们的创新培训计划中的成功。