Lung Repair and Regeneration Consortium Administrative Coordinating Center

肺修复与再生联盟行政协调中心

• 批准号: 8788546
• 负责人: Scott M Palmer
• 金额: $ 131.44万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8788546
• 关键词: Acute Lung Injury; Advisory Committees; Affect; Applications Grants; Area; Award; Basic Science; Bioethics; Bioinformatics; Biology; Biometry; Chronic Obstructive Airway Disease; Clinical Research; Collaborations; Communication; Complement; Custom; Development; Education; Educational process of instructing; Electronic Mail; Ensure; Face; Fostering; Funding; Future; Future Generations; Goals; Grant; Grant Review; Growth; Guidelines; Hamman-Rich syndrome; Hand; Home environment; Human Resources; Individual; Industry; Information Technology; Institutes; Instruction; Intellectual Property; Investigation; Knowledge; Language; Lead; Leadership; Lung; Lung diseases; Mentors; Modeling; Monitor; National Heart, Lung, and Blood Institute; Natural regeneration; Online Systems; Patients; Peer Review; Persons; Physicians; Pilot Projects; Process; Pulmonology; Qualifying; Reagent; Regenerative Medicine; Regulatory Affairs; Reporting; Research; Research Activity; Research Ethics; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Role; Science; Site; Stem Cell Research; Structure; Teleconferences; Testing; Tissue Engineering; Training; Training Activity; Training and Infrastructure; Translational Research; United States National Institutes of Health; Update; Vision; Web communication; career; design; effective therapy; experience; improved; injury and repair; innovation; lung injury; lung regeneration; lung repair; meetings; member; multidisciplinary; novel; programs; research and development; response; skills; skills training; stem; stem cell biology; success; tool; tool development; translational medicine; virtual; web site

In response to RFA-HL-12-010, the DTMI proposes to serve as the Administrative Coordinating Center (ACC) for the Lung Repair and Regeneration Consortium (LRRC). This proposal brings together a highly qualified team of individuals, infrastructure, and core resources to fully support the goals of the consortium to advance lung regeneration and repair research. Our ACC Leadership Team includes well-established individuals who bring considerable experience coordinating and leading multicenter research networks, soliciting and reviewing grant application, developing educational training activities, and who possess in- depth knowledge of lung biology and regeneration. The Leadership Team is complemented by the ACC Core Resources Team who will provide scientific support to the Research Centers (RCs) in the areas of bioinformatics, biostatistics, research ethics, intellectual property, and regulatory affairs. Additionally, our ACC structure includes an ACC Senior Advisory Committee comprised of successful independent investigators in lung biology, stem cell research, and tissue engineering who will provide additional guidance to the ACC to ensure a structure that meets the needs of the LRRC. In short, this leadership structure is made up of investigators who understand the complexity of lung biology, can speak the language of basic research, and bring a wealth of experience coordinating multisite networks. They will create an ACC that facilitates communication throughout the LRRC and efficiently accomplish all of the LRRC goals. The ACC Operational Team will consist of project leadership, web and communications expertise, and will be drawn from within the DTMI. These operational resources from within the DTMI have a proven record of web-based network website creation, grant solicitation and oversight, and the development of trainee education programs including a Master's program in Clinical Research co-taught at Duke and the NIH. In summary, the DTMI will foster innovative, streamlined, and highly successful approaches to study coordination, research subaward administration, and web-based communication as the ACC. In order to accomplish these goals, we have developed three specific aims for this consortium: 1) To organize and conduct consortium communication, including teleconferences, in-person meetings, and creation of a web-based, virtual home for the LRRC that synergizes all network functions, 2) To solicit and administer awards to the RCs for collaborative research and tool development projects, and 3) To support the development ofthe SDC and SDC committee to train a future generation of researchers in lung regeneration and repair.

作为对RFA-HL-12-010的回应，DTMI建议作为行政协调中心 (ACC)肺修复和再生联盟（LRRC）这一建议汇集了一个高度 由个人、基础设施和核心资源组成的合格团队，以充分支持联盟的目标， 推进肺再生和修复研究。我们的ACC领导团队包括 个人谁带来了相当多的经验协调和领导多中心研究网络， 征求和审查赠款申请，开展教育培训活动，以及谁拥有- 深入了解肺生物学和再生。领导团队由ACC核心补充 资源团队，将在以下领域为研究中心（RC）提供科学支持 生物信息学、生物统计学、研究伦理、知识产权和法规事务。此外，我们的 行政协调会的结构包括行政协调会高级咨询委员会， 肺生物学、干细胞研究和组织工程的研究人员，他们将提供额外的指导 以确保结构符合LRRC的需要。简而言之，这种领导结构是 由了解肺部生物学复杂性的研究人员组成，可以说基本的语言， 研究，并带来丰富的经验，协调多站点网络。他们将创建一个ACC， 有助于整个LRRC的通信，并有效地实现所有LRRC目标。行政协调会 运营团队将由项目领导、网络和通信专业人员组成， 从DTMI内部。DTMI内部的这些运营资源具有基于网络的 建立网络网站，争取和监督赠款，以及发展受训者教育 包括在杜克和NIH共同教授的临床研究硕士课程。总的来说， DTMI将促进创新的、精简的和非常成功的方法来研究协调， 研究子奖管理，并基于网络的通信作为ACC。为了实现这些 目标，我们为这个联盟制定了三个具体目标：1）组织和开展联盟 通信，包括电话会议、面对面会议以及创建基于网络的虚拟家庭 对于协同所有网络功能的LRRC，2）征求和管理对RC的奖励， 合作研究和工具开发项目，以及3）支持SDC的开发， SDC委员会将培养下一代肺再生和修复研究人员。