Pathogenesis and Diagnosis of Multiple System Atrophy

核心B数据核心- Peter C.奥布莱恩博士，主要研究者 数据中心负责收集、输入、管理和分析MSA数据库。具体而言，核心将促进数据收集，确保捕获数据的质量，管理不断发展的数据库，包括进行例行备份。其向PI和其他研究者报告数据库的状态，并在项目结束时对其他数据进行统计分析和数据库存档。 数据核心将为计划项目的数据管理提供支持。特别是，数据核心将为项目1，MSA快速进展的预测因素提供统计支持，PI：Sid Gilman，M.D.数据核心成员还将为以下项目提供数据分析和/或编辑临床数据分析文件的帮助：项目4，MSA中自主神经功能衰竭的诊断、病理生理学和治疗研究，PI：菲利普低，医学博士，项目3：MSA的模型和实验治疗，PI：Eliezer Masliah，医学博士。此外，核心B维护的数据库将包含核心C（死亡MSA患者的尸检结果）和核心D（样本和DNA的可用性）的信息。

Core B Data Core - Peter C. O'Brien, Ph.D., Principal Investigator The Data Core is responsible for the collection, entry, management, and analysis of the MSA database. Specifically, the Core will facilitate the collection of data, it assures the quality of the captured data, it manages the evolving database, including doing routine backups. It reports to the PI and the other investigators on the state of the database, it conducts the statistical analyses other data and archival of the database at the conclusion of the project. The Data Core will provide support for data management for the program project. In particular, the data core will provide statistical support for Project 1, Predictors of Rapid Progression in MSA, PI: Sid Gilman, M.D. Data Core members will also provide assistance with data analyses and/or compile analysis files of clinical data for the following projects: Project 4, Studies on Diagnosis, Pathophysiology, and Treatment of Autonomic Failure in MSA, PI: Phillip Low, M.D., and Project 3: Models and Experimental Treatment for MSA, PI: Eliezer Masliah, M.D.. Furthermore, the data base maintained by Core B will house information from Cores C (autopsy results of deceased MSA patients) and Core D (availability of samples and DNA).