Integrated Endocrine and Metabolic Research Training

描述（由申请人提供）：贝斯以色列女执事医疗中心内分泌培训项目，由Barbara Kahn博士指导，每年培养4名内分泌学，糖尿病和代谢研究领域的医学博士，医学博士/博士或博士博士后。该计划的目标是将受训人员培养成独立的研究人员，他们将在科学调查中脱颖而出，并可以在主要大学医学院获得教职。内分泌项目的研究人员是一群经验丰富的研究人员，他们参与了肥胖、糖尿病、甲状腺生物学、核受体作用、神经内分泌学和信号转导的研究。该学院由基础和临床科学家组成，他们共同训练研究员在分子和生理水平上研究问题。他们的多份联合出版物，他们的三个项目资助，以及他们作为波士顿地区nih资助的肥胖中心和糖尿病内分泌研究中心的一部分的多个研究核心设施，都表明了教师的合作性质。正在开始博士后工作或更高级的学员将有机会从教师的综合和集体专业知识中学习，包括激素作用，基因表达，脂肪细胞生物学，动物生理学，内分泌和代谢疾病的复杂转基因和基因靶向方法，神经解剖学和神经生理学，人类受试者研究以及新治疗方式的策略。学员在T32的支持下工作1-3年。他们在获得独立资金方面有着出色的记录，许多前受训人员已被提升为教师职位。这些受资助的研究人员现在参与培训这个项目和其他内分泌学、糖尿病和代谢项目的研究员。自上次竞争性续期以来，该部门增加了新的，有才华的教师，扩大了研究空间和核心设施。该项目得到了贝斯以色列女执事医疗中心基因组学、蛋白质组学、质谱学、生物统计学和生物信息学以及转基因小鼠的核心设施的大力支持。该计划进一步规范了其负责任和道德研究行为的课程。学员的成功反映了内分泌培训项目的卓越品质。

DESCRIPTION (provided by applicant): The Endocrine Training Program at Beth Israel Deaconess Medical Center, directed by Dr. Barbara Kahn, trains four MD, MD/PhD or PhD postdoctoral fellows per year in the research areas of endocrinology, diabetes, and metabolism. The goal of the program is to foster the development of trainees into independent investigators who will excel in scientific investigation and can obtain faculty positions at major university medical schools. The research faculty for the endocrine program is an experienced group of investigators involved in the study of obesity, diabetes, thyroid biology, nuclear receptor action, neuroendocrinology, and signal transduction. The faculty is comprised of basic and clinical scientists who work together to train fellows to investigate questions at both the molecular and physiological levels. The collaborative nature of the faculty is made evident by their multiple joint publications, their three Program Project Grants and their multiple research core facilities as part of Boston area NIH-funded Obesity Centers and Diabetes Endocrinology Research Centers. Trainees who are either beginning their postdoctoral work or are more advanced are provided an opportunity to learn from the integrated and collective expertise of the faculty in hormone action, gene expression, adipocyte biology, animal physiology, sophisticated transgenic and gene targeting approaches to endocrine and metabolic disorders, neuroanatomy and neurophysiology, research in human subjects, and strategies for novel treatment modalities. Trainees are supported by the T32 for 1-3 years. They have an outstanding record of obtaining independent funding and a number of former trainees have been promoted to faculty positions. These funded investigators now participate themselves in training fellows in this and other Programs in Endocrinology, Diabetes and Metabolism. Since the last competitive renewal of this grant, the Division has added new, talented faculty and expanded its research space and core facilities. The program is strongly supported by core facilities at Beth Israel Deaconess Medical Center in Genomics, Proteomics, Mass Spectrometry, Biostatistics and Bioinformatics, and Transgenic Mouse Generation. The program has further formalized its curriculum in the responsible and ethical conduct of research. The success of the trainees reflects the outstanding quality of this Endocrine Training Program.