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TAS::75 0886::TAS MEDICINAL CHEMISTRY FOR NEUROTHERAPEUTICS PROGRAM (MCNP)

TAS::75 0886::TAS MEDICINAL CHEMISTRY FOR NEUROTHERAPEUTICS PROGRAM (MCNP)
塔斯马尼亚州::75 0886::塔斯马尼亚州神经治疗药物化学项目 (MCNP)
批准号：
9104030
负责人：
KEITH BARNES
金额：
$76.29万
依托单位：
ALBANY MOLECULAR RESEARCH, INC.
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-08-17 至 2016-08-16
来源：
https://reporter.nih.gov/project-details/9104030
关键词：
Basic ScienceBiological AssayChemical StructureChemicalsCollaborationsContractorContractsCountryDataData AnalysesHumanIndividualInformation SystemsInstructionModelingModificationParticipantPharmaceutical ChemistryPharmaceutical PreparationsPharmacology and ToxicologyPropertyResearch PersonnelServicesTimeUnited States National Institutes of HealthWorkanaloghigh throughput screeningimprovednervous system disorderprogramsresearch studysmall molecule

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中文摘要
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英文摘要
The NIH is developing a Medicinal Chemistry for Neurotherapeutics Program (MCNP) to generate new optimized drugs leads for nervous system disorders. High-throughput screens and basic research studies have led to the discovery of many small molecule compounds with activity in models of nervous system disorders. Some of these compounds have the potential to be transformed into drugs for human use, with chemical modifications to improve their potency and pharmacological properties. The MCNP will support collaborations between a contracted medicinal chemistry facility and researchers (Contributors) with bioactive small molecule compounds and bioactivity assays to develop optimized drug leads.
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