Instruments for Micro-Magnetic Stimulation of the Brain in Animals

描述（由申请人提供）：我们建议评价显微磁刺激（mMS）探头（一种新的脑刺激技术）的功能、MRI和生物相容性。此外，已经证明，所施加的MS场的取向（相对于可兴奋组织）提供了传统电刺激所看不到的神经元元件的独特激活，这是一种可以用来改善实验或治疗目标的特性。这些信息将用于开发动物神经科学研究的新产品线。 这些发现将为进一步探索MS作为临床和临床前应用的前瞻性工具提供理论基础，该工具将由FHC商业化，FHC是一家拥有42年成功营销研究神经科学市场历史的公司。目标是进一步刺激MS技术的发展以及对大脑功能的理解。

DESCRIPTION (provided by applicant): We propose to evaluate the functionality, MRI- and bio-compatibility of probes for microscopic magnetic stimulation (mMS), a new brain stimulation technology. Moreover, it has been demonstrated that the orientation of the applied ¿MS fields (relative to the excitable tissue) provides unique activation of neuronal elements not seen with traditional electrical stimulation, a property that can be leveraged to improve experimental or therapeutic goals. This information will be used to develop a new product line for animal neuroscience research. These findings will provide a rationale for the further exploration of ¿MS as a prospective tool for clinical and preclinical applications which will be commercialized by FHC, a company with a 42-year history of successfully marketing to the research neuroscience market. The goal will be to further stimulate both development of ¿MS technology as well as the understanding of brain function.