Research Training Program in Nutrition, Obesity and Metabolic Disorders

描述（由申请人提供）：本提案的目的是为培养致力于研究营养与代谢之间相互作用的学术生涯的博士科学家提供资金。更具体地说，了解、预防和治疗代谢性疾病，包括糖尿病、肥胖和相关并发症，如非酒精性脂肪性肝病（NAFLD）、非酒精性脂肪性肝炎（NASH）和肾脏疾病。由于这些疾病在美国日益流行，在这些领域培养未来研究人员的重要性是显而易见的。这一建议的基本原理是基于一种坚定的信念，即营养是最重要的之一，如果不是最重要的

DESCRIPTION (provided by applicant): The objective of this proposal is to obtain funds for the training of PhD scientists committed to academic careers that have a research focus integrating the interaction between nutrition and metabolism. More specifically to understand, prevent, and treat metabolic diseases which include diabetes, obesity and associated complications, such as nonalcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and kidney disease. The importance of training future researchers in these areas is evident due to the growing epidemic of these disorders in the United States. The rationale for this proposal is based on the firm belief that nutrition is one of the most significant, if not the significant environmental factor that may be modified to prevent, delay or ameliorate obesity and metabolic disorders. This proposal therefore seeks funds to train the next generation of nutrition research investigators to address an understanding of metabolism and metabolic dysfunction at the molecular, cellular, whole body and/or population levels. Support is requested for five pre-doctoral training slots for each of the proposed five years. All trainees are first admitted to a graduate degree program at the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy, located on the Health Science Campus of Tufts University, and, after one year of coursework and laboratory rotations are eligible to be admitted to the the proposed training program. Acceptance into the training program is predicated upon outstanding academic and research achievement during the first year. Each of the faculty mentors have appointments within the Health Science Campus and will provide exemplary research training to pre-doctoral students interested in the broad research areas of obesity, diabetes, metabolism, digestive diseases, endocrinology, genomics and gene therapy, epidemiology, and related diseases of the kidney and pancreas.