Research Training Program in Metabolism, Obesity and Type 2 Diabetes

新陈代谢、肥胖和 2 型糖尿病研究培训项目

• 批准号: 10634853
• 负责人: DANIEL Holland BESSESEN
• 金额: $ 8.06万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10634853
• 关键词: Metabolism; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Research Training; Training Programs

Project Summary/Abstract The problems of obesity and type 2 diabetes are some of the most common conditions affecting Americans. There is a critical need to train the next generation of MD and PhD investigators who will address these public health challenges with innovations in basic, clinical and translational sciences. We believe that the University of Colorado, Anschutz Medical Campus (UCAMC) is well positioned to provide the training needed to produce the next generation of scientists addressing these areas. We are seeking support for 6 positions (3 post-doctoral trainees to be supported for 2 years each) in the new Research Training Program in Metabolism, Obesity and Type 2 Diabetes (RTPMOD) at the UCAMC. The strength of the proposed RTPMOD lies the outstanding faculty, state of the art facilities and programs at the UCAMC and a robust pipeline of applicants. The 16 members of the Training Faculty are productive well-funded investigators many of whom are nationally recognized leaders in their fields of study who collectively have $12,710,098 in current research funding (direct costs current year). A number of affiliate and junior faculty mentors have been identified to ensure a rich training environment and a robust pipeline of future mentors for the program. The UCAMC is host to the Colorado Clinical Translational Science Institute, the Colorado Nutrition Obesity Research Center and the Anschutz Health & Wellness Center to name just a few of the resources that will support the proposed training. Over the last 10 years RTPMOD faculty have trained 93 post-doctoral fellows (current and past). Of those who completed training, 62% hold faculty positions, with 36 Assistant, 4 Associate and 2 full Professors. Over the last 5 years, we have trained 42 training grant eligible post-doctoral fellows (current and past). Of those who have completed training, 83% are currently in a research related or research intensive positions. Of the 42 training grant eligible trainees, 41% received K or equivalent (VA, ACS) awards and 14% are Co-Investigators on R level or equivalent awards. Applicants for the RTPMOD will come from a range of clinical fellowship programs at UCAMC, our new clinical Obesity Medicine Fellowship, and the Physician Scientist Training Program track within our Internal Medicine Training Program. PhD applicants will come from local and national recruitment efforts. MD and PhD applicants will be selected though a rigorous recruitment process to identify those with the greatest promise to pursue an independent research career. In addition to an intensive mentored research experience, trainees will gain formal training in metabolism, obesity and type 2 diabetes and team science. The program will be administered by an experienced Program Director supported by an Executive Committee with input from a committee to support the recruitment and retention of trainees from under-represented minorities and an independent Institutional Advisory Board. In this revised application we have addressed the concerns raised in the prior review and hope that RTPMOD will be now viewed as a program that is likely to provide outstanding training for post-doctoral fellows seeking a long term independent research career in metabolism, obesity or type 2 diabetes research.

项目总结/摘要 肥胖和2型糖尿病是影响美国人的一些最常见的疾病。 有一个迫切需要培训下一代的MD和博士研究人员谁将解决这些公众 基础科学、临床科学和转化科学创新带来的健康挑战。我们认为， 科罗拉多，安舒茨医学院（UCAMC）是很好的定位，以提供所需的培训，以产生 下一代科学家致力于这些领域。我们正在寻求6个职位的支持（3个博士后 学员将得到支持2年每）在新的研究培训计划在代谢，肥胖和 2型糖尿病（RTPMOD）在UCAMC。拟议的RTPMOD的优势在于优秀的教师， 最先进的设施和程序在UCAMC和申请人的强大管道的状态。的16名成员 培训学院是富有成效、资金充足的研究人员，其中许多人是国家公认的领导者 在他们的研究领域谁共同拥有$12，710，098在当前的研究经费（直接成本本年度）。 已经确定了一些附属和初级教师导师，以确保丰富的培训环境和 为该计划提供强大的未来导师管道。UCAMC是科罗拉多临床翻译中心的主办单位。 科学研究所、科罗拉多营养肥胖研究中心和安舒茨健康与保健中心 仅举几个支持拟议培训的资源。在过去的10年里，RTPMOD 学院培养了93名博士后研究员（现任和前任）。在完成培训的人中，62%持有 教师职位，有36名助理，4名副教授和2名正教授。在过去的五年里，我们已经培训了42名 有资格获得培训补助金的博士后研究员（现任和前任）。在完成培训的人中，83%是 目前在研究相关或研究密集的职位。在42名符合培训补助金资格的学员中， 获得K或同等（VA，ACS）奖励，14%是R级或同等奖励的合作研究者。 RTPMOD的申请人将来自UCAMC的一系列临床奖学金项目，我们的新临床研究项目 肥胖医学奖学金和内科医生科学家培训计划 培训计划。博士申请人将来自当地和国家的招聘工作。MD和PhD申请人 将通过严格的招聘程序进行筛选，以确定那些最有希望追求 独立的研究生涯。除了密集的指导研究经验，学员将获得正式的 代谢、肥胖和2型糖尿病以及团队科学方面的培训。该计划将由一个 经验丰富的项目总监，由执行委员会提供支持， 招聘和留住代表性不足的少数群体的受训人员， 咨询委员会。在这份修订后的申请中，我们解决了先前审查中提出的问题，并希望 RTPMOD现在将被视为一个可能为博士后提供出色培训的项目 在代谢、肥胖或2型糖尿病研究方面寻求长期独立研究生涯的研究员。