Identifying Ecologically Valid Intervention Opportunities to Reduce Opioid Injection Drug Use in Southwestern Pennsylvania
Identifying Ecologically Valid Intervention Opportunities to Reduce Opioid Injection Drug Use in Southwestern Pennsylvania
批准号:
9266851
负责人:
Jessica Griffin Burke
金额:
$15.43万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-09-01 至 2018-08-31
关键词:
AddressAdvisory CommitteesAlcohol or Other Drugs useAppalachian RegionAreaAttentionCodeCollaborationsCommunitiesComorbidityCountyDataDependenceDevelopmentDisease OutbreaksDistressDrug AddictionDrug abuseDrug usageEconomic ConditionsEpidemicFoundationsFundingGoalsGrantGrowthHIVHIV InfectionsHIV/HCVHealthHealth PersonnelHealth ProfessionalHepatitis CHeroinHeroin DependenceHospitalizationHospitalsHot SpotInjection of therapeutic agentInpatientsInterventionInterviewInvestigationLawyersLinkMeasuresMental HealthMethodsModelingOpioidOverdosePatientsPatternPennsylvaniaPilot ProjectsPlanet MarsPovertyPreventionPreventive InterventionProbabilityPublic HealthRecording of previous eventsResearchResearch MethodologyResearch Project GrantsResourcesRuralSamplingTimeWorkexperienceinformantinjection drug useinsightmeetingsnovelopioid abuseopioid useopioid use disorderprogramsresponsesocialsuccessful intervention
中文摘要
摘要
英文摘要
ABSTRACT
Opioid abuse rates are exploding in rural and economically distressed communities in the Appalachian region
and associated health consequences, including Hepatitis C (HCV) and HIV, are also on the rise. The harmful
impact of opioids have received national attention, yet the drivers of the spread of opioid use disorders (OUD)
and overdose across communities are not yet understood. In addition, the intertwined relationship between
injection opioid drug use and co-morbidities including Hepatitis C and HIV infection necessitate further
investigation to inform integrated prevention and intervention efforts. Few studies have used an in-depth,
ecologically valid approach to collect information from local community stakeholders with contextually specific
experience addressing the epidemic. The overall goal of this one-year planning research grant (in response to
RFA-DA-16-015) is to examine contextually- and temporally-specific patterns of the opioid epidemic in the
Northern Appalachian Region of Southwestern Pennsylvania using complementary quantitative and qualitative
approaches. We propose to use a mixed methods approach incorporating spatial analyses of OUD and
overdose hospitalizations and qualitative data from local stakeholders to better understand the spread of opioid
injection drug use in the ten counties that make up the Northern Appalachian Region of Southwestern
Pennsylvania. The Specific Aims of this proposal are: (1) To characterize the growth and spread of opioid drug
abuse, dependence, and overdose and associated co-morbidities (HCV and HIV) over time and space and (2)
To identify resources and intervention opportunities associated with opioid drug abuse, dependence, and
overdose and associated co-morbidities within one “hot spot” community. We will combine 16 years of well-
resolved spatial data with qualitative data to be collected using a community engaged approach and in-depth
interviews in a purposefully sampled target case community. We will start by examining hospital patient spatial
data at the ZIP code level to measure the geographic growth and spread of OUD and two comorbid conditions
(HCV & HIV) as measured by 64 quarters of inpatient hospitalization data (from 2000 through 2015). We will
identify specific attributes of areas (e.g., economic conditions) that facilitate spread over time across ZIP
codes, and distinguish the temporal scale of these impacts. Spatial random effects models and posteriors from
these models will be used to identify one “case” community (defined by 2015 ZIP code boundaries) with the
greatest predicted probability of comorbid epidemic outbreak. In this case community we will identify and
engage key stakeholders, including clinicians & treatment providers (focused on opioids, HCV, and HIV), and
others (e.g. former opioid injection users) identified through snowball sampling. We will use qualitative
interviews with 20 informants to identify drivers of the intersecting epidemics and existing resources and novel
intervention opportunities. This work will lay the foundation for larger action-oriented research and planning
efforts addressing opioid injection drug use, HCV and HIV in the Appalachian region.
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会议论文
Academic-Community Partnership to Address Maternal and Child Health in Allegheny
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批准号:8212402
-
项目类别:
-
资助金额:$3.0万
-
财政年份:2011
-
负责人:Jessica Griffin Burke
-
依托单位:
Academic-Community Partnership to Address Maternal and Child Health in Allegheny
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批准号:8455721
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项目类别:
-
资助金额:$3.0万
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财政年份:2011
-
负责人:Jessica Griffin Burke
-
依托单位:
Patterns of Substance Use Among HIV Positive and Negative Aging MSM
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批准号:7686285
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项目类别:
-
资助金额:$15.15万
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财政年份:2008
-
负责人:Jessica Griffin Burke
-
依托单位:
Patterns of Substance Use Among HIV Positive and Negative Aging MSM
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批准号:7585013
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项目类别:
-
资助金额:$15.15万
-
财政年份:2008
-
负责人:Jessica Griffin Burke
-
依托单位:
海外基金