FASEB SRC on Liver Biology: Fundamental Mechanisms and Translational Applications

 描述（由申请人提供）： 目前的申请寻求美国实验生物学学会联合会（FASEB）关于“肝脏生物学：基本机制和转化应用”的科学研究会议的部分支持。在过去的20年里，该会议每两年举行一次，现在被公认为世界上首屈一指的会议，涵盖涉及肝脏的基础科学研究的各个方面。会议将于2016年6月26日至7月1日在佛罗里达州西棕榈滩举行。会议的主要目标是i）整合肝脏生物学不同领域提供的研究进展，以促进国家和国际规模的新合作项目，ii）鼓励初级和早期研究人员，妇女和少数民族科学家进行肝脏研究，以确保肝病和生物学研究保持活力，以及iii）通过基础和临床研究人员的相互作用，加速将肝脏生物学的基本进展转化为新的临床治疗方法。这些目标将通过具体的方案战略来实现。该计划分为九个主要会议，包括来自45位受邀演讲者的演讲。此外，这些会议将容纳多个简短的“最新”会谈，这些会谈将被选择代表肝脏研究中最重要和最及时的研究进展。将优先考虑初级、少数民族和妇女调查员。该计划还提供海报和“会见专家”会议，用于一对一的对话，以及在整个逗留期间演讲者和与会者之间进行非正式但亲密的科学交流的其他机会。虽然会议将保持涵盖广泛的基础科学和转化主题的传统-包括肝脏器官发生，肝胆调节， 健康和疾病中的基因表达、肝再生、肝损伤和纤维化、肝干细胞和再生医学-由于其日益增长的相关性，将特别关注肝代谢和脂肪肝以及肝癌。对于所有主题，重点是最近和当前发现的翻译应用。总之，该计划整合了肝脏健康和疾病的基础和应用方面最相关和最及时的主题，以促进科学交流，传播，教育和合作以及转化为患者护理。

 DESCRIPTION (provided by applicant): The current application seeks partial support for the Federation of American Societies for Experimental Biology (FASEB) Science Research Conference on "Liver Biology: Fundamental Mechanisms and Translational Applications". For the past 20 years, this meeting has been held biennially and is now recognized as the world's premier conference covering all aspects of basic science research involving the liver. The conference will be held from June 26-July 1, 2016, in West Palm Beach, Florida. The main goals of the conference are to i) integrate the research advances offered by disparate areas of liver biology in order to foster new collaborative projects on both national and international scale, ii) encourage junior and early stage investigators, women and minority scientists to pursue liver research to ensure that the study of hepatic disease and biology remains vigorous and iii) accelerate translation of fundamental advances in liver biology into novel clinical treatments through the interactions of basic and clinical researchers. These goals will be achieved through specific programmatic strategies. The program is divided into nine major sessions and includes presentations from forty-five invited speakers. In addition, these sessions will accommodate multiple short 'late-breaking' talks that will be chosen to represent the most significant and timely research advances in liver research. Preference will be given to junior, minority and women investigators. The program also provides poster and "meet-the-expert" sessions for one-on- one dialogue and several additional opportunities for informal, yet intimate scientific exchange among speakers and attendees throughout the stay. While the conference will keep the tradition of covering a wide range of basic science and translational topics - including liver organogenesis, regulation of hepatobiliary gene expression in health and disease, liver regeneration, liver injury and fibrosis, liver stem cells and regenerative medicine - there will be particular focus on hepatic metabolisms and fatty liver as well as liver cancer due to their growing relevance. For all topics, emphasis is given to translational application of recent and current discoveries. In summary, the program integrates the most relevant and timely topics in basic and applied aspects of liver health and disease to promote scientific exchange, dissemination, education and collaboration and translation to patient care.