Development of Psychopathology: From Brain and Behavioral Science to Intervention

 产品说明：此应用程序是在精神病理学的发展T32培训计划的5年更新：从大脑和行为干预。“精神和药物滥用障碍更有可能在生命早期出现. [and]事实上，是年轻人的主要非传染性疾病”（Insel，2014年;第1727页）。因此，早期识别风险过程和早期干预至关重要。随着该领域从行为转向神经发育，该培训计划也在不断发展，以反映人类大脑发育的重要进展。这个跨学科计划的主要目标是培养科学家，他们将（1）促进对精神病理学发展和维持的神经生物学和心理社会机制的知识状态，以及（2）将基础研究的发现转化为预防和改善精神病理学和促进心理健康的预防性干预措施的发展。该培训计划提供多学科科学的个人指导，并辅以教学活动。为每个研究员制定个性化的培训计划，并在每个学期重新评估。在过去的五年里，我们已经明确地将我们的重点转移到增加对神经生物学，心理生理学，遗传学和心理社会机制的多学科研究的培训。自2010年最后一次更新以来，11名博士前学员中有3名（27%）和5名博士后中有2名（40%）来自神经科学项目。在过去的十年中，我们的24个前和12个博士后学员中有超过75%继续通过学术研究和教学为该领域做出贡献。四分之一的受训人员代表不同的少数民族群体，67%为女性。四个predoc继续在这个T32培训;其他3名前predoc学员正在他们的论文工作; 3正在做他们所需的临床实习。其余14名前predoc学员都已完成博士学位; 6名是学术心理学系教师职位的研究人员; 2名是博士后研究员; 4名从事临床服务，咨询，教学和监督的组合，2名正在从事临床工作。在12名博士后研究员中，3名继续接受培训; 9名前博士后中有7名仍积极参与研究和教学。培训计划成功的其他重要指标是学员的出版记录[predocs：141篇论文，平均值=5.9;中位数=5;博士后：157篇论文，平均值=13.08;中位数=13]和他们从个人职业发展奖（F30，F31，K 01，K99），R型赠款（例如，R34、R21、R 00）和基础（例如，脑行为研究基金）。本次更新申请建议每年再次支持4名博士前培训生和3名博士后研究员。我们未来五年的主要目标是继续培养研究科学家，他们可以发现并将临床神经科学的基本知识转化为减少精神病理学的干预措施。我们将特别关注研究领域标准（RDoC），资助写作和专业发展。

 DESCRIPTION: This application is for a 5-year renewal of the T32 Training Program in the Development of Psychopathology: From Brain and Behavior to Intervention. "Mental and substance abuse disorders are more likely to arise early in life...[and] are, in fact, the predominant noncommunicable disorders of young people" (Insel, 2014; p. 1727). Therefore, early identification of risk processes and early intervention are crucial. As the field has been shifting from a behavioral to a neurodevelopmental focus, this training program also has been evolving to reflect important advances in human brain development. The major thrust of this interdisciplinary program is to produce scientists who will (1) contribute to the state of knowledge about neurobiological and psychosocial mechanisms underlying the development and maintenance of psychopathology, and (2) translate findings from basic research to the development of empirically-based interventions for the prevention and amelioration of psychopathology and for the promotion of mental health. The training program provides individual mentoring in multidisciplinary science complemented by didactic activities. A personalized training plan is developed for each fellow and re-evaluated each semester. In the last five years, we have explicitly shifted our focus to increasing training on multidisciplinary research on neurobiological, psychophysiological, genetic, and psychosocial mechanisms underlying psychiatric illness. Since the last renewal in 2010, three of the 11 (27%) predoctoral trainees and two of the five postdocs (40%) have come from neuroscience programs. In the last decade, over 75% of our 24 pre- and 12 post-doctoral trainees have continued to contribute to the field through scholarly research and teaching. A quarter of trainees represent diverse ethnic minority groups and 67% have been female. Four predocs continue in training on this T32; 3 other former predoc trainees are working on their dissertations; 3 are doing their required clinical internship. All 14 remaining former predoc trainees have completed their PhDs; 6 are researchers in faculty positions in academic psychology departments; 2 are postdoctoral fellows; 4 do a combination of clinical service, consulting, teaching, and supervision, and 2 are doing clinical work. Of the 12 postdoctoral fellows, 3 continue in training; 7 of the 9 former postdocs are still actively involved in research and teaching. Other important indicators of the training program's success are trainees' publication records [predocs: 141 papers, mean=5.9; median=5; postdocs: 157 papers, mean=13.08; median =13] and their acquisition of research funding from individual career development awards (F30, F31, K01, K99), R-type grants (e.g., R34, R21, R00), and foundations (e.g., Brain Behavior Research Fund). This renewal application proposes to again support 4 predoctoral trainees and 3 postdoctoral fellows annually. Our primary goals for the next five years are to continue to develop research scientists who can discover and translate basic knowledge from clinical neuroscience into interventions for reducing psychopathology. We will especially focus on the Research Domain Criteria (RDoC), grant writing, and professional development.