Native American Research Internship (NARI) Summer Program in Diabetes, Obesity and Metabolism

项目摘要/摘要 在美国，2900万人(占美国人口的9.3%)患有糖尿病，且比例偏低 少数族裔，如美洲印第安人和阿拉斯加原住民(AI/AN)，有不成比例的高发病率 糖尿病(AI/AN为15.9%，非西班牙裔和白人为7.6%)。消除健康差距，如 由于AI/AN中的糖尿病和肥胖症需要确定、招募、教育和培训 美国不同的才华横溢的科学家群体。在犹他大学，我们建立了一个原住民 美国研究实习生(NARI)计划，使用社区参与和原住民原则 长辈、教职员工和学生指导，目标是增加AI/AN在生物医学中的代表性 科学，从而减少健康差距。NARI本科生的参与者将获得研究、文化和 与忠诚的社区成员和著名科学家一起进行专业指导和培训。到目前为止， 来自24个部落国家、29所学院/大学和19个家乡州的58名参与者参加了这次活动 在节目中。所有人都成功完成了项目要求，28人参加了为期2个夏天的活动。 在58名参与者中，14名(24%)是目前正在攻读理科学位的本科生，44名 (76%)已完成理科学士学位。没有人从大学辍学。10(17%) 在NARI计划之后，参与者曾在生物医学科学领域担任研究助理。vt.在.的基础上 在获得本科学位后，19名(33%)的参与者继续在 健康/科学领域：10人被生物医学研究生项目录取；8人被医学研究生项目录取 学校；和1都被录取(他获得了细胞和分子生物学的硕士学位，现在是3年级 医科学生)。目前，NARI受训人员的研究经验仅限于产妇和 儿童健康、心血管疾病、肺病和血液病，但不在糖尿病或肥胖症领域- 相关研究。在最近的一项调查中，我们目前的NARI参与者报告说，糖尿病和肥胖症是 他们的家人最关心的健康问题，大多数参与者的家人都患有糖尿病 (63%)或肥胖(76%)。通过这项提议，我们将扩大现有的NARI计划，使其包括研究 糖尿病和肥胖症研究(NARI-NIDDK)的经验和教育培训 困扰人工智能/人工智能人群的担忧。

PROJECT SUMMARY/ABSTRACT In the United States, 29 million people (9.3% of the US population) have diabetes and underrepresented minorities, such as American Indian and Alaskan Natives (AI/AN), have a disproportionally high prevalence of diabetes (15.9% for AI/AN compared to 7.6% for non-Hispanic and whites). Eliminating health disparities such as diabetes and obesity among AI/AN requires the identification, recruitment, education, and training of a diverse group of talented scientists in the US. At the University of Utah, we have established a Native American Research Internship (NARI) program that uses the principles of community engagement and Native elders, faculty, and student guidance with the goal of increasing AI/AN representation in the biomedical sciences and thus reducing health disparities. NARI undergraduate participants receive research, cultural, and professional mentorship and training with committed community members and renowned scientists. To date, 58 participants representing 24 tribal nations, 29 colleges/universities, and 19 home states, have participated in the program. All have successfully completed the program requirements with 28 participating for 2 summers. Of the 58 participants, 14 (24%) are currently undergraduates working towards a science degree, and 44 (76%) have completed a bachelor’s degree in science. No one has dropped out of college. Ten (17%) participants have worked in the biomedical sciences as research assistants following the NARI program. Upon obtaining their undergraduate degree, 19 (33%) of the participants are continuing their education in the health/science fields: 10 were accepted into a biomedical graduate program; 8 were accepted into medical school; and 1 was accepted to both (he obtained his MS in Cell and Molecular Biology and is now a 3rd year medical student). The current research experiences for NARI trainees is limited to the fields of maternal and child health, cardiovascular, pulmonary, and hematologic disease, but not in the field of diabetes or obesity- related research. In a recent survey, our current NARI participants reported that diabetes and obesity were the top health concerns of their families and the majority of participants have family members affected by diabetes (63%) or obesity (76%). Through this proposal, we will expand the existing NARI program to include research experiences and educational training in diabetes and obesity research (NARI-NIDDK), two major health concerns that plague AI/AN populations.