Interdisciplinary Training Program in Metabolism

 描述（由申请人提供）：目前需要培养一批医生和博士研究人员，他们将把他们的专业活动的重要组成部分用于了解肥胖、糖尿病及其许多并发症的病理生理学和治疗。本申请代表了犹他州大学医学院代谢跨学科培训项目的第一个竞争性更新申请。我们正在请求支持两个博士后职位和三个博士前职位在此更新应用程序。该计划继续建立在犹他州大学代谢研究的独特优势之上，该研究跨越了一系列模式生物的基础和机制研究，以及人类的转化研究。新成立的糖尿病和代谢中心（DMC）在犹他州的大学是这个培训计划的基础，并支持招聘，保留和创新的教师合作，专注于糖尿病，肥胖和代谢。该培训计划的关键要素包括：1）在基础和临床研究方面基于导师的强有力培训，2）严格的教学课程，包括代谢核心课程以及研究方法和资助写作方面的具体培训，3）与内部和外部演讲者一起重点关注代谢的系列讲座，4）根据个人发展计划提供量身定制的职业指导，以确保成功过渡到职业生涯的下一阶段，以及4）提供演讲和外联机会，以发展沟通技能。培训教师包括33名DMC教职员工，来自医学院内的七个部门和内科系内的六个部门的稳定的校外资金和动态研究计划。从内分泌学和心脏病学的奖学金培训计划中招募临床合格的学员，并在全国范围内招募博士博士后。博士前候选人从犹他州大学生物化学和分子生物学的联合项目中招募。培训计划由健康科学高级副总裁办公室管理，并由执行委员会监督，该委员会由两名共同主要研究者和三名共同主任组成，他们都是具有良好跟踪记录和坚定承诺指导学员的研究者。

 DESCRIPTION (provided by applicant): There is an ongoing need to train a cadre of physician and PhD investigators who will devote a significant component of their professional activity to understanding the pathophysiology and treatment of obesity, diabetes and its many complications. This application represents the first competitive renewal application for the Interdisciplinary Training Program in Metabolism at the University of Utah School of Medicine. We are requesting support for two postdoctoral positions and three predoctoral positions in this renewal application. This program continues to build on unique strengths in metabolism research at the University of Utah that spans basic and mechanistic investigation across a range of model organisms to translational studies in humans. The newly established Diabetes and Metabolism Center (DMC) at the University of Utah is the foundation of this training program as and supports recruitment, retention, and collaboration of innovative faculty focused on diabetes, obesity and metabolism. Key elements in this training program include 1) strong mentor-based training in basic and clinical investigation, 2) rigorous didactic curriculum including a core curriculum in metabolism as well as specific training in research methodologies and grant writing, 3) a lecture series focused on metabolism with internal and external speakers, 4) tailored career mentoring with individual development plans to ensure a successful transition to the next stage of their career, and 4) presentation and outreach opportunities to develop communication skills. The training faculty comprises 33 DMC faculty members with stable extramural funding and dynamic research programs from seven departments within the School of Medicine and six divisions within the Department of Internal Medicine. Clinically qualified trainees are recruited from fellowship training programs in Endocrinology and Cardiology, and PhD postdocs are recruited nationally. Predoctoral candidates are recruited from the combined programs in Biological Chemistry and Molecular Biology at the University of Utah. The training program is administered through the Office of the Senior Vice President for Health Sciences, and will be overseen by an executive committee comprising the two Co-Principal Investigators and three Co-Directors, all of whom are investigators with strong track records of and uncompromising commitment to mentoring trainees.