Interdisciplinary Training Program in Metabolism

 描述(申请人提供)：目前需要培训一批医生和博士研究人员，他们将在专业活动中投入大量精力，了解肥胖、糖尿病及其许多并发症的病理生理学和治疗方法。这份申请是犹他大学医学院新陈代谢跨学科培训计划的第一次竞争性续签申请。在这次续签申请中，我们请求支持两个博士后职位和三个博士后职位。该计划继续建立在犹他大学新陈代谢研究的独特优势之上，该研究涵盖了一系列模型生物的基础和机械研究，以及人类的翻译研究。犹他大学新成立的糖尿病和代谢中心(DMC)是这一培训计划的基础，并支持招聘、保留和协作专注于糖尿病、肥胖症和新陈代谢的创新型教员。这一培训计划的主要内容包括1)在基础和临床研究方面以导师为基础的强有力的培训，2)严格的教学课程，包括新陈代谢的核心课程以及研究方法和拨款申请的具体培训，3)与内部和外部演讲者一起举办以新陈代谢为重点的系列讲座，4)通过个人发展计划进行量身定做的职业指导，以确保他们成功过渡到职业生涯的下一阶段，以及4)展示和拓展机会以发展沟通技能。培训教员由33名DMC教员组成，他们拥有稳定的外部资金和来自医学院内七个系和内科内六个科的动态研究计划。临床合格的实习生从内分泌学和心脏病学的奖学金培训计划中招募，博士后在全国范围内招募。博士前候选人是从犹他大学生物化学和分子生物学的联合项目中招募的。培训方案通过卫生科学高级副总裁办公室管理，并将由一个执行委员会监督，该执行委员会由两名联合首席调查员和三名联席主任组成，他们都是调查人员，在指导受训人员方面有着良好的记录和坚定的承诺。

 DESCRIPTION (provided by applicant): There is an ongoing need to train a cadre of physician and PhD investigators who will devote a significant component of their professional activity to understanding the pathophysiology and treatment of obesity, diabetes and its many complications. This application represents the first competitive renewal application for the Interdisciplinary Training Program in Metabolism at the University of Utah School of Medicine. We are requesting support for two postdoctoral positions and three predoctoral positions in this renewal application. This program continues to build on unique strengths in metabolism research at the University of Utah that spans basic and mechanistic investigation across a range of model organisms to translational studies in humans. The newly established Diabetes and Metabolism Center (DMC) at the University of Utah is the foundation of this training program as and supports recruitment, retention, and collaboration of innovative faculty focused on diabetes, obesity and metabolism. Key elements in this training program include 1) strong mentor-based training in basic and clinical investigation, 2) rigorous didactic curriculum including a core curriculum in metabolism as well as specific training in research methodologies and grant writing, 3) a lecture series focused on metabolism with internal and external speakers, 4) tailored career mentoring with individual development plans to ensure a successful transition to the next stage of their career, and 4) presentation and outreach opportunities to develop communication skills. The training faculty comprises 33 DMC faculty members with stable extramural funding and dynamic research programs from seven departments within the School of Medicine and six divisions within the Department of Internal Medicine. Clinically qualified trainees are recruited from fellowship training programs in Endocrinology and Cardiology, and PhD postdocs are recruited nationally. Predoctoral candidates are recruited from the combined programs in Biological Chemistry and Molecular Biology at the University of Utah. The training program is administered through the Office of the Senior Vice President for Health Sciences, and will be overseen by an executive committee comprising the two Co-Principal Investigators and three Co-Directors, all of whom are investigators with strong track records of and uncompromising commitment to mentoring trainees.