NanoSystems Biology Cancer Center Nano/micro Fabrication and Materials (NM2) Core

共享资源核心。 纳米系统生物学癌症中心纳米/微制造和材料（NM 2）核心 摘要： 纳米/微米制造和材料（NM 2）核心是NSBCC定制设计的核心资源。通过 通过提炼各个项目具体目标的研究需求，我们确定了一套研究工具 4个项目中至少有3个项目需要，或至少有2个项目大量使用。这些 工具喙向下进入（1）用于基于微芯片的平台的微/纳米制造的资源和执行 相关测定的资源;（2）用于纳米颗粒表征的资源;以及（3）用于肽和 生物分子的制备、修饰和纯化。我们将这些共同的研究需求视为 机会，以提高我们的项目的成本效益，同时也通过促进跨- 项目之间的思想、知识和研究人员的交流。在核心主任的指导下 博士吉姆希思（加州理工学院）和共同主任博士杨植信（加州大学洛杉矶分校）这些研究的需要，以及由此产生的 教育和科学机会，告知中央政府的组成和行政结构， 管理NM 2核心，在加州理工学院和加州大学洛杉矶分校的位置。

Shared Resources Cores. NanoSystems Biology Cancer Center Nano/micro Fabrication and Materials (NM2) Core ABSTRACT: The Nano/micro fabrication and Materials (NM2) Core is a custom-designed Core Resource of the NSBCC. By distilling out the research needs of the individual Project Specific Aims, we identified a set of research tools that were needed by least 3 out of the 4 projects, or which were heavily used by at least 2 projects. These tools beak down into (1) resources for micro/nano fabrication of microchip-based platforms and the execution of the associated assays; (2) resources for nanoparticle characterization; and, (3) resources for peptide and biomolecular preparation, modification, and purification. We view these common research needs as an opportunity to increase the cost-efficiency of our Projects, while also accelerating progress by promoting cross- fertilization of ideas, knowledge, and researchers between the projects. Under the direction of Core Director Dr. Jim Heath (Caltech) and co-director Dr. Young Shik Shin (UCLA) these research needs, and the resultant educational and scientific opportunities, inform the composition and administrative structure of a centrally managed NM2 core, with locations at both Caltech and UCLA.