Clinical and Laboratory Research Training for Surgical Oncologists

描述（由申请人提供）：目前癌症研究中科学发现的快速发展，特别是在细胞、基因组和分子水平上，为基础科学发现的快速临床应用提供了前所未有的机会。这一进展将通过为一组已经走向学术领导地位的外科肿瘤学家提供严格的基础和临床研究培训来优化。该计划的具体目标是为这一高度选择的个人群体提供科学思想和技术的正式培训。共有六个培训名额， 学员追求高度抢手的亚专科奖学金培训外科肿瘤学，以及普通外科居民致力于癌症研究的职业生涯。甄选过程将确定并匹配最合格的申请人，而不考虑他们是内部还是外部候选人。学员将选择进入实验室研究轨道或临床研究轨道。每个研究员将被引导从我们的参与教师名单中选择一位高级导师/导师，他们都在实验室或临床癌症研究中表现出杰出的成就记录，以及成功的实习生导师的既定记录。培训期间不受临床职责的干扰，包括研究伦理的正式培训以及针对个人兴趣和能力的额外强制性课程。所有受训人员都被指派一个个人研究金委员会，负责对受训人员的研究提出批评，监测在独立调查职业生涯方面取得的长期进展，并协助选择适当的课程工作。对于临床研究跟踪学员，研究培训环境包括临床研究的研究生培训计划，其中可以攻读硕士或博士课程。该计划在招聘代表性不足的少数民族方面取得了巨大成功，这是由于我们的临床学员中杰出的榜样和妇女和少数民族的广泛代表性，以及本提案中概述的其他战略。通过这种方式，该计划旨在产生一个高度精选的学术外科肿瘤学家群体，他们将开发原创和重要的研究计划，并在癌症研究界提供强有力的领导。

DESCRIPTION (provided by applicant): The current rapid pace of scientific discovery in cancer research, particularly at the cellular, genomic, and molecular levels, offers unprecedented opportunities for rapid clinical application of basic scientific findings. This progress will be optimized by providing rigorous basic and clinical research training to a select group of surgical oncologists who are already directed towards academic leadership. The Specific Aim of this program is to provide formal training in scientific thought and technique to this highly select group of individuals. A total of six training slots are competitively awarded to trainees pursuing highly sought-after subspecialty fellowship training Surgical Oncology, as well as General Surgery residents committed to careers in cancer research. The selection process will identify and match the most qualified applicant, without regard to whether they are an internal or an external candidate. Trainees will elect to enter either the Laboratory Research Track or the Clinical Research Track. Each fellow will be guided to choose a senior preceptor/mentor from our list of participating faculty, all of whom have demonstrated an outstanding record of achievement in either laboratory or clinical cancer research, as well as an established record of successful trainee mentorship. The training period is uninterrupted by clinical duties, and includes formal training in research ethics as well as additional mandatory course work tailored to individual interests and capabilities. All trainees are assigned an Individual Fellowship Committee charged with critiquing the trainee's research, monitoring long-term progress towards an independent investigative career, and aiding in the selection of appropriate course work. For Clinical Research Track trainees, the research training environment includes the Graduate Training Program in Clinical Investigation, in which either Masters or PhD programs may be pursued. The program has achieved outstanding success in the recruitment of underrepresented minorities, owing to outstanding role models and broad representation of women and minorities among our clinical trainees, as well as additional strategies outlined in this proposal. In this manner, the program is designed to generate a highly selected group of academic Surgical Oncologists who will develop original and significant research programs and provide strong leadership within the cancer research community.