Clinical and Laboratory Research Training for Surgical Oncologists

肿瘤外科医师临床和实验室研究培训

• 批准号: 8100310
• 负责人: Steven D Leach
• 金额: $ 37.28万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-26 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8100310
• 关键词: Clinical Research; Laboratory Research; Research Training; Surgical Oncologist

DESCRIPTION (provided by applicant): The current rapid pace of scientific discovery in cancer research, particularly at the cellular, genomic, and molecular levels, offers unprecedented opportunities for rapid clinical application of basic scientific findings. This progress will be optimized by providing rigorous basic and clinical research training to a select group of surgical oncologists who are already directed towards academic leadership. The Specific Aim of this program is to provide formal training in scientific thought and technique to this select group of individuals. Two trainees per year will be competitively selected among trainees pursuing highly sought-after subspecialty fellowship training in either General or Thoracic Surgical Oncology. The selection process will identify and match the most qualified applicant, without regard to whether they are an internal or an external candidate. Trainees will elect to enter either the Laboratory Research Track or the Clinical Research Track. Each fellow will be guided to choose a senior preceptor/mentor from our list of participating faculty, all of whom have demonstrated an outstanding record of achievement in either laboratory or clinical cancer research, as well as an established record of successful trainee mentorship. The formal research training program begins after the required 18 months of post-residency surgical oncology training (our priority) or after the PG3 year of surgical residency, and would last for 2-3 consecutive years. This training period is uninterrupted by clinical duties, and includes formal training in research ethics as well as additional mandatory course work tailored to individual interests and capabilities. All trainees are assigned an Individual Fellowship Committee charged with critiquing the trainee's research, monitoring long-term progress towards an independent investigative career, and aiding in the selection of appropriate course work. The research training environment includes the graduate program in Cellular and Molecular Medicine, in which selected trainees may be awarded Ph.D. degrees, as well as the Graduate Training Program in Clinical Investigation, in which either Masters or PhD programs may be pursued. The specific recruitment of underrepresented minorities to this program is enhanced by broad representation of women and minorities among our Surgical Oncology and Thoracic Surgery faculty and proactive strategies described in the grant. In this manner, the program is designed to generate a highly selected group of General and Thoracic Surgical Oncologists who will develop original and significant research programs and provide academic leadership throughout the surgical and oncologic communities. RELEVANCE: Our proposed training program seeks to support formal research training for young surgical oncologists who will pursue careers in either laboratory or clinical cancer research, as they prepare for leadership roles in academic surgical oncology. This training grant will be a vital component in the national transition to a streamlined training program for academic surgical oncologists.

描述（由申请人提供）：目前癌症研究中科学发现的快速发展，特别是在细胞、基因组和分子水平上，为基础科学发现的快速临床应用提供了前所未有的机会。这一进展将通过为一组已经走向学术领导地位的外科肿瘤学家提供严格的基础和临床研究培训来优化。该计划的具体目标是为这一特定群体提供科学思想和技术的正式培训。每年将有两名学员在普通或胸外科肿瘤学方面进行备受追捧的亚专科奖学金培训的学员中进行竞争性选择。选择过程将识别并匹配最合格的申请人，而不考虑他们是内部候选人还是外部候选人。学员将选择进入实验室研究轨道或临床研究轨道。每个研究员将被引导从我们的参与教师名单中选择一位高级导师/导师，他们都在实验室或临床癌症研究中表现出杰出的成就记录，以及成功的实习生导师的既定记录。正式的研究培训计划开始后，所需的18个月的住院医师后外科肿瘤学培训（我们的优先事项）或后PG 3年的外科住院医师，并将持续2-3连续年。该培训期间不受临床职责的干扰，包括研究伦理的正式培训以及针对个人兴趣和能力的额外强制性课程。所有受训人员都被指派一个个人研究金委员会，负责对受训人员的研究提出批评，监测在独立调查职业生涯方面取得的长期进展，并协助选择适当的课程工作。研究培训环境包括细胞和分子医学的研究生课程，其中选定的学员可以被授予博士学位。学位，以及临床研究的研究生培训计划，其中无论是硕士或博士课程可以追求。在我们的外科肿瘤学和胸外科教师和补助金中描述的积极主动的战略之间的妇女和少数民族的广泛代表性增强了代表性不足的少数民族的具体招聘。通过这种方式，该计划旨在产生一个高度选择的普通和胸外科肿瘤学家群体，他们将开发原创和重要的研究项目，并在整个外科和肿瘤学社区提供学术领导。 相关性：我们提出的培训计划旨在支持年轻的外科肿瘤学家的正式研究培训，他们将在实验室或临床癌症研究中追求职业生涯，因为他们准备在学术外科肿瘤学中担任领导角色。这项培训补助金将是国家向学术外科肿瘤学家精简培训计划过渡的重要组成部分。