Clinical and Laboratory Research Training for Surgical Oncologists

肿瘤外科医师临床和实验室研究培训

• 批准号: 10477943
• 负责人: Lei Zheng
• 金额: $ 44.78万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-26 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10477943
• 关键词: Clinical Research; Laboratory Research; Research Training; Surgical Oncologist

SUMMARY The current rapid pace of scientific discovery in cancer research, particularly in the areas of cancer genetics, tumor biology, immunology and tumor microenvironment, offers unprecedented opportunities for rapid clinical application of basic scientific findings. This progress will be optimized by providing rigorous basic and clinical research training to a select group of surgical oncology trainees who are already directed towards academic leadership. The Specific Aim of this program is to provide formal training in scientific thought and technique to this highly select group of individuals. A total of six training slots are competitively awarded to trainees pursuing highly sought-after subspecialty fellowship training in surgical oncology, as well as general surgery residents committed to careers in cancer research. For this renewal application, six “faculty participating units” will be formed and each is focused on the research training in one malignant disease field. The participating unit is formed by a multidisciplinary group of senior faculty preceptors together with clinical faculty members who will serve as co-mentors for our trainees. This structure is designed to position trainees to engage in “team science”. In the current era of specialization in highly sophisticated areas of research, the optimal structure for impactful contributions by surgeon scientists is through a team approach. The trainee selection process is an interactive process involving both candidates of trainees and faculty members and will match the most qualified applicants with the most suitable faculty members. Both internal and external candidates are equally considered. Trainees will elect to enter either the Laboratory Research Track or the Clinical Research Track. The training period is uninterrupted by clinical duties and includes formal training in research ethics as well as additional mandatory course work tailored to individual interests and capabilities. The participating units will guide each trainee in their units to form an Individual Advisory Committee, which will meet regularly to critique the trainee's research, monitor their long-term progress towards an independent investigative career, and aid in the selection of appropriate course work. In addition, training in the basic science research, leadership, and grant writing will be required. The program has achieved outstanding success in the recruitment of underrepresented minorities, owing to outstanding role models and broad representation of women and minorities among our clinical trainees, as well as additional strategies outlined in this proposal. Moreover, a formal evaluation of faculty and the program by trainees is implemented. Thus, in the renewal application, the program is further strengthened to nourish a highly selected group of academic surgical oncologists who will develop original and significant research programs and provide strong leadership within the cancer research community.

总结 目前癌症研究的科学发现速度很快，特别是在癌症遗传学领域， 肿瘤生物学、免疫学和肿瘤微环境，为快速临床治疗提供了前所未有的机会。 基本科学发现的应用。这一进程将通过提供严格的基础和临床 为一组选定的外科肿瘤学受训者提供研究培训，这些受训者已经被定向为学术研究人员。 领导该计划的具体目标是提供科学思想和技术的正规培训， 这群经过精挑细选的人共有六个培训名额，透过竞争方式， 在外科肿瘤学和普通外科学方面备受欢迎的亚专科奖学金培训 致力于癌症研究的居民。对于本次更新申请，六个“教职员工参与单位” 将成立，每个都集中在一个恶性疾病领域的研究培训。与会 该单位是由一个多学科小组的高级教师导师连同临床教员 他们将担任我们学员的共同导师。这种结构的目的是让受训者从事 团队科学在当前高度复杂的研究领域专业化的时代， 外科医生科学家做出有影响力贡献的结构是通过团队方法。实习生选拔 过程是一个互动的过程，涉及学员和教师的候选人，并将匹配 最合格的申请人与最合适的教师。内部和外部候选人都是 同样考虑。学员将选择进入实验室研究轨道或临床研究 轨道培训期间不受临床职责的干扰，包括研究伦理学方面的正式培训， 以及根据个人兴趣和能力量身定制的额外必修课程。各参建单位 将指导每个学员在各自的单位成立一个个人咨询委员会，该委员会将定期开会， 批评受训者的研究，监督他们走向独立调查事业的长期进展， 并协助选择适当的课程作业。此外，基础科学研究方面的培训， 领导力和赠款写作将是必需的。该计划取得了巨大的成功， 征聘任职人数不足的少数族裔，因为他们具有杰出的榜样和广泛的代表性 妇女和少数民族的问题，以及本建议中概述的其他战略。 此外，还实施了对教员和学员的正式评估。因此，在更新 应用，该计划进一步加强，以滋养一个高度选择的学术外科群体 肿瘤学家谁将开发原创和重要的研究计划，并提供强有力的领导， 癌症研究团体。