Jamboxx: Interactive Respiratory Therapy through Music and Gaming

 描述（由申请人提供）：本项目的目标是开发一种用于呼吸治疗的新型器械，该器械使用交互式游戏和音乐来鼓励患者依从性。为了保持肺部健康，许多手术后患者以及四肢瘫痪和其他脊髓损伤、高水平运动神经元疾病（如肌萎缩侧索硬化症（ALS）和多发性硬化症（MS））以及囊性纤维化等疾病的患者 进行常规呼吸治疗。这些治疗技术用于帮助加强和拉伸肺部周围的肌肉，锻炼横膈膜，并放松粘液积聚，以促进改善肺功能。改善肺功能有助于降低肺炎和其他呼吸道疾病的发生率，这是脊髓损伤患者死亡的主要原因，也是术后患者中最普遍和最致命的医院询问感染（HAI）。这些治疗技术通常缺乏反馈和激励，需要用户依赖助手，并且对于具有有限移动性的用户来说变得费力和平凡，从而导致低患者依从性。我们的目标是通过添加游戏组件来提高患者的依从性，为用户提供吸引人的激励，以坚持他们的处方治疗程序。这项工作建立在我们发明的Jamboxx之上：一种免提呼吸控制数字乐器，专为四肢瘫痪或其他运动神经元疾病的用户设计。我们的目标是扩展Jamboxx的功能，以创建一个商业上可行的和经过验证的产品，用于改善呼吸治疗。该器械在改善需要常规呼吸治疗的长期门诊患者和需要术后呼吸调节的短期住院患者的依从性方面具有显著潜力。改善治疗依从性可以改善脊髓损伤和其他需要呼吸康复的慢性疾病患者及其家人的长期结局和日常功能。为此，我们将创建一个产品和一套跨平台的小游戏，供患者使用，模拟一些常用的呼吸治疗技术。一旦确定了临床功能，该设备将在医院和门诊环境中进行严格的评估，为后续的临床试验做准备。

 DESCRIPTION (provided by applicant): The goal of this project is to develop a novel device for respiratory therapy that uses interactive gaming and music to encourage patient compliance. In order to maintain pulmonary health, many post-operative surgery patients as well as people with quadriplegia and other spinal cord injuries, high-level motor neuron diseases such as amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), and disorders like cystic fibrosis undergo routine respiratory therapy. These therapy techniques are used to help strengthen and stretch the muscles around the lungs, exercise the diaphragm, and loosen mucus build-up to promote improved lung function. Improved lung function can help reduce the incidence of pneumonia and other respiratory illness, a leading cause of mortality among spinal cord injury patients and the most prevalent and most fatal hospital inquired infection (HAI) among post-operative patients. These therapy techniques often lack feedback and incentive, require the user to depend on an assistant, and become strenuous and mundane for users with limited mobility resulting in low patient compliance. We aim to improve patient compliance by adding a gaming component to provide users with an engaging incentive to adhere to their prescribed therapy routine. This work builds on our invention of the Jamboxx: a hands free breath controlled digital musical instrument designed for accessibility by users with quadriplegia or other motor neuron diseases. We aim to extend the functionality of the Jamboxx to create a commercially viable and proven product for improving respiratory therapy. This device has significant potential for improving compliance in both long-term outpatient users requiring routine respiratory therapy and short-term inpatient users requiring post-op respiratory conditioning. Improved therapy compliance can lead to improvements in long term outcomes as well as daily functioning for people with spinal cord injuries and other chronic disease requiring respiratory rehabilitation, as well as their families. To do this, we will create a product and a suite of mini-games with cross platform availability for patient use that will mimic a number of commonly prescribed respiratory therapy techniques. Once clinical functionality has been established, the device will enter into rigorous evaluation in both a hospital and outpatient setting in preparation for a subsequent clinical trial.