Jamboxx: Interactive Respiratory Therapy through Music and Gaming

Jamboxx：通过音乐和游戏进行互动呼吸治疗

• 批准号: 9140618
• 负责人: Michael DiCesare
• 金额: $ 22.5万
• 依托单位: MY MUSIC MACHINES, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9140618
• 关键词: Amyotrophic Lateral Sclerosis; Breathing; Bronchitis; Chronic Disease; Clinical; Clinical Trials; Collaborations; Cystic Fibrosis; Development; Devices; Disease; Environmental air flow; Evaluation; Exercise; Family; Feedback; Goals; Hand; Health; Hospitals; Incentives; Incidence; Infection; Inpatients; Lead; Lung; Lung diseases; Manufacturer Name; Measures; Medical center; Monitor; Motor Neuron Disease; Mucous body substance; Multiple Sclerosis; Muscle; Music; Operative Surgical Procedures; Outcome; Outpatients; Patients; Phase; Pneumonia; Population; Postoperative Period; Preparation; Price; Production; Quadriplegia; Rehabilitation therapy; Respiratory Diaphragm; Respiratory Therapy; Respiratory physiology; Sales; Spinal cord injury; Spinal cord injury patients; Spirometry; Stretching; Tablets; Techniques; Testing; Time; User Compliance; Work; base; children with cystic fibrosis; commercialization; compliance behavior; conditioning; daily functioning; design; digital; game development; improved; improved outcome; instrument; invention; medical schools; mortality; novel; pressure; prototype; public health relevance; respiratory; routine therapy; usability

 DESCRIPTION (provided by applicant): The goal of this project is to develop a novel device for respiratory therapy that uses interactive gaming and music to encourage patient compliance. In order to maintain pulmonary health, many post-operative surgery patients as well as people with quadriplegia and other spinal cord injuries, high-level motor neuron diseases such as amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS), and disorders like cystic fibrosis undergo routine respiratory therapy. These therapy techniques are used to help strengthen and stretch the muscles around the lungs, exercise the diaphragm, and loosen mucus build-up to promote improved lung function. Improved lung function can help reduce the incidence of pneumonia and other respiratory illness, a leading cause of mortality among spinal cord injury patients and the most prevalent and most fatal hospital inquired infection (HAI) among post-operative patients. These therapy techniques often lack feedback and incentive, require the user to depend on an assistant, and become strenuous and mundane for users with limited mobility resulting in low patient compliance. We aim to improve patient compliance by adding a gaming component to provide users with an engaging incentive to adhere to their prescribed therapy routine. This work builds on our invention of the Jamboxx: a hands free breath controlled digital musical instrument designed for accessibility by users with quadriplegia or other motor neuron diseases. We aim to extend the functionality of the Jamboxx to create a commercially viable and proven product for improving respiratory therapy. This device has significant potential for improving compliance in both long-term outpatient users requiring routine respiratory therapy and short-term inpatient users requiring post-op respiratory conditioning. Improved therapy compliance can lead to improvements in long term outcomes as well as daily functioning for people with spinal cord injuries and other chronic disease requiring respiratory rehabilitation, as well as their families. To do this, we will create a product and a suite of mini-games with cross platform availability for patient use that will mimic a number of commonly prescribed respiratory therapy techniques. Once clinical functionality has been established, the device will enter into rigorous evaluation in both a hospital and outpatient setting in preparation for a subsequent clinical trial.

 描述（由申请人提供）：该项目的目标是开发一种用于呼吸治疗的新型设备，该设备使用互动游戏和音乐来鼓励患者依从性。为了保持肺部健康，许多术后患者以及患有四肢瘫痪和其他脊髓损伤、肌萎缩侧索硬化症 (ALS) 和多发性硬化症 (MS) 等高级运动神经元疾病以及囊性纤维化等疾病的患者 接受常规呼吸治疗。这些治疗技术用于帮助加强和伸展肺部周围的肌肉，锻炼膈肌，放松粘液积聚，以促进改善肺功能。改善肺功能有助于减少肺炎和其他呼吸道疾病的发生率，肺炎和其他呼吸道疾病是脊髓损伤患者死亡的主要原因，也是术后患者中最常见和最致命的医院询问感染（HAI）。这些治疗技术通常缺乏反馈和激励，需要用户依赖助手，并且对于行动不便的用户来说变得费力且乏味，导致患者依从性低。我们的目标是通过添加游戏组件来提高患者的依从性，为用户提供有吸引力的激励，以遵守他们规定的治疗程序。这项工作建立在我们发明的 Jamboxx 的基础上：一种免提呼吸控制的数字乐器，专为患有四肢瘫痪或其他运动神经元疾病的用户而设计。我们的目标是扩展 Jamboxx 的功能，创造一种商业上可行且经过验证的产品，以改善呼吸治疗。该设备对于提高需要常规呼吸治疗的长期门诊用户和需要术后呼吸调节的短期住院用户的依从性具有巨大的潜力。改善治疗依从性可以改善脊髓损伤和其他需要呼吸康复的慢性病患者及其家人的长期结果和日常功能。为此，我们将创建一款产品和一套具有跨平台可用性的迷你游戏，供患者使用，模仿许多常用的呼吸治疗技术。一旦临床功能确定，该设备将在医院和门诊接受严格的评估，为后续的临床试验做准备。