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Effect of Treatment Dose on Childhood Obesity

治疗剂量对儿童肥胖的影响

基本信息

批准号：
9127691
负责人：
Kerri N Boutelle
金额：
$ 69.45万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-01 至 2021-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9127691
关键词：
Address Adult Affect Aftercare Age Behavior Therapy Behavioral Body Size Body Weight Body Weight decreased Child Child Rearing Childhood Control Groups Cost Savings Data Diet Dietary intake Dose Educational Status Effectiveness Family Gender Goals Health Hour Individual Intervention Manuals Measures Mediator of activation protein Methods Obesity Outcome Overweight Parents Physical activity Pilot Projects Population Randomized Randomized Controlled Trials Recommendation Recruitment Activity Research Schedule Target Populations Techniques Testing Third-Party Payer Time Training Translating United States Visit Weight base cost cost effective cost effectiveness effective intervention effective therapy executive function follow-up indexing intervention program nutrition obesity in children programs psychosocial public health relevance randomized trial self help skills standard care therapy development treatment effect treatment program treatment response trial comparing

项目摘要

DESCRIPTION (provided by applicant): One in every three children is overweight or obese. Overweight and obesity in childhood is associated with negative health and psychosocial consequences for children and adults. To date, the most successful weight loss treatment for children who are overweight or obese are family-based behavioral programs (FBT) that are delivered in separate parent and child groups over a 6-month period. FBT is fairly intensive and access to these programs can be challenging. We have developed a guided self-help treatment which is based on FBT (gshFBT), and provides a self-help manual to parents and children along with guidance in the form of 20-minute check-in visits every other week. Our studies show that gshFBT is feasible and acceptable to families, decreases body weight in children and parents compared to a delayed treatment control, and that it produces similar weight losses compared to the more intensive FBT. However, all of our studies with gshFBT were conducted with children who were 85%BMI-98%BMI and to date, this method has not been tested with heavier children. Additionally, our pilot studies only included a 6-month follow-up timepoint and longer follow-up is needed. Thus, the objective of this study is to conduct a fully powered randomized controlled trial comparing gshFBT with FBT in children across the overweight and obese weight spectrum. We will recruit, randomize and treat 160 overweight/obese children and their parents and assess them at baseline, post-treatment, and 6- and 18-months follow-up. Primary and secondary aims are as follows. Primary Aim 1: Compare the effect of gshFBT and FBT on the target child's weight over the two years of the study. Primary Aim 2: Evaluate the cost effectiveness of gshFBT as compared to FBT. Secondary Aim 1: Determine the extent to which the gshFBT and FBT affects parent BMI, parenting skills, and parent and child physical activity and dietary intake. Additionally, as exploratory aims, we will evaluate moderators and mediators of gshFBT and FBT including executive functioning and parenting style. This application is a critical next step in the development of treatments for overweight and obese children, and could provide a treatment that is less intensive, less costly and has the potential to be provided to a larger proportion of the population.