Patched gene family control of epidermal development and cancer

皮肤是人体最大的器官，起着防止感染和脱水的屏障作用。从临床的角度来看，我们需要知道如何再生皮肤，以更好地愈合伤口和治疗烧伤。我们已经确定了一种调节皮肤干细胞的遗传途径，这项研究将向我们展示皮肤发育和再生的机制，以及我们可以用来增加临床愈合的可能操作。

The skin is the largest organ in the body and functions as a barrier against infection and dehydration. From a clinical perspective we need to know how to regenerate skin for better wound healing and the treatment of burns. We have identified a genetic pathway that regulates the stem cells of the skin and this research will show us the mechanism whereby the skin develops and regenerates, as well as the possible manipulations we can use to increase healing in the clinic.