45th Annual Meeting of the American Aging Association

 描述（由申请人提供）：我们正在申请资金，以支持美国老龄化协会第45届年会将于6月3日至6月6日在埃奇沃特酒店和贝尔港会议中心，西雅图，华盛顿举行。这次会议是老年医学研究的主要会议之一，也是美国唯一一次由专业会员组织主办的年度会议，其重点是老龄化的生物医学问题。会议的主题是“对抗老化：抗老化医学的终极目标”。年龄主席Matt Kaeberlein博士与年龄计划委员会（安森、Buffenstein、纳尔逊、Perez-Olsen和Promislow博士）、会议主席和年龄执行委员会共同组织科学计划。总体目标是召集来自多个学科的科学家和学员参加论坛，介绍和批判性辩论老龄化研究的最新发现，并激发参与者之间的前瞻性思维和合作。资金要求帮助支付1）受邀演讲者和2）有价值的年轻科学家（学生，博士后研究员和初级教师）的旅费，他们可以从接触该领域的领导者中受益，展示他们的研究成果，并有机会做出贡献并从该领域的专家那里获得反馈。这次会议的具体目标是：（a）召集基础和临床科学家组成一个基础广泛的论坛，介绍利用新方法、发现新机制和有潜力开发可提高健康生活质量和寿命的治疗方法的研究结果;（B）突出会议最近未涉及的重要研究领域;（c）鼓励公开讨论和辩论;和d）强调综合和转化研究的机会。受邀演讲者包括老龄化和相关学科的著名科学家，他们因其科学和激发辩论的能力而被选中。在选择会议主题时，特别努力保持老龄化研究的会议主题为“最终的替代医学”，突出具有明显转化潜力的基础研究，以改善人们的健康老龄化。这些包括最近关于全身因素和衰老的备受瞩目的工作，包括循环激素和可能被治疗操纵的分子;整个会议致力于旨在识别和验证促进健康老龄化的干预措施的工作;以及一个题为从实验室到诊所的会议：健康老龄化的转化方法，将呈现从临床环境中应用老龄化研究发现的第一次努力的结果。这些更多的翻译会议将通过会议补充，这些会议将直接关注该领域快速发展领域的重要基本进展，如细胞稳态机制和健康老龄化的保守机制。我们认为，所有的专题讨论会的主题是及时的，并应激发讨论，合作努力和可能的治疗目标的发展。

 DESCRIPTION (provided by applicant): We are requesting funds to support the 45th Annual Meeting of the American Aging Association to be held June 3rd to June 6th at the Edgewater Hotel and Bell Harbor Conference Center, Seattle, Washington. This meeting is one of the premier meetings for biogerontological research and is the only annual meeting sponsored by a professional membership organization in the United States that limits its focus to biomedical issues in aging. The theme of the meeting is "Targeting Aging: The Ultimate in Preventative Medicine". Dr. Matt Kaeberlein, President of AGE, together with the AGE Program Committee (Drs. Anson, Buffenstein, Nelson, Perez-Olsen, and Promislow), Session Chairs, and the AGE Executive Board organize the scientific program. The overall objective is to convene scientists and trainees from multiple disciplines in a forum for presentation and critical debate of the lates discoveries in aging research and to stimulate forward thinking and collaboration among participants. Funds are requested to help cover travel expenses of 1) invited speakers and 2) meritorious junior scientists (students, postdoctoral fellows and junior faculty) who can benefit from exposure to the leaders of the field, present their research findings and have the opportunity to contribute and get feedback from experts in the field. The specific goals of this meeting are a) to assemble a broad-based forum of basic and clinical scientists to present findings that utilize novel methods, uncover new mechanisms and have potential for development of therapeutics that may enhance quality and length of healthy life; b) to highlight important research areas not recently covered at meetings; c) to encourage open discussion and debate; and d) to emphasize integrative and translational research opportunities. The invited speakers include renowned scientists in aging and related disciplines selected for their science and ability to stimulate debate. When selecting session topics, a particular effort was placed on keeping with the meeting theme of aging research as "The Ultimate Preventative Medicine" by highlighting basic research with clear translational potential for improving healthy aging in people. These include recent high profile work on Systemic Factors and Senescence, including circulating hormones and molecules that can perhaps be manipulated therapeutically; an entire session devoted to work aimed at identifying and validating Interventions That Promote Healthy Aging; and a session titled From bench to clinic: Translational approaches to healthy aging that will present results from the first efforts to apply discoveries from aging research in a clinical setting. These more translational sessions will be complemented by sessions focused squarely on important fundamental advances in the fast moving areas of the field such as Mechanisms of Cellular Homeostasis and Conserved mechanisms of healthy aging. We believe that all of the symposia topics are timely, and should stimulate discussion, collaborative endeavors and the development of possible therapeutic targets.