45th Annual Meeting of the American Aging Association

 描述(申请人提供)：我们正在申请资金，以支持将于6月3日至6月6日在华盛顿州西雅图埃奇沃特酒店和贝尔港会议中心举行的美国老龄协会第45届年会。这次会议是生物老年学研究的主要会议之一，也是美国唯一一个由专业会员组织主办的、将重点放在老龄化生物医学问题上的年度会议。会议的主题是“以衰老为目标：预防医学的终极目标”。AGE主席Matt Kaeberlein博士与AGE计划委员会(Anson、Buffenstein、Nelson、Perez-Olsen和Promislow博士)、会议主席和AGE执行委员会共同组织了这项科学计划。总体目标是召集来自多个学科的科学家和受训人员在一个论坛上介绍老龄化研究的最新发现并进行批判性辩论，并鼓励参与者之间的前瞻性思维和合作。请拨资金帮助支付1)特邀演讲者和2)有功绩的初级科学家(学生、博士后研究员和初级教员)的旅费，他们可以受益于接触该领域的领导人，介绍他们的研究成果，并有机会作出贡献并从该领域的专家那里获得反馈。这次会议的具体目标是：a)召集基础和临床科学家的一个基础广泛的论坛，介绍利用新方法、发现新机制并有潜力开发可提高健康生命质量和长度的疗法的研究结果；b)突出最近未在会议上涉及的重要研究领域；c)鼓励公开讨论和辩论；以及d)强调综合和翻译研究机会。受邀的演讲者包括老龄化和相关学科的知名科学家，他们因其科学和激发辩论的能力而被选中。在选择会议主题时，特别努力与老龄化研究的会议主题“终极预防医学”保持一致，强调具有明显翻译潜力的基础研究，以改善人们的健康老龄化。其中包括最近关于系统性因素和衰老的高调工作，包括也许可以通过治疗操纵的循环激素和分子；致力于识别和验证促进健康老龄化的干预措施的整个会议；以及题为从长凳到临床：健康老龄化的翻译方法的会议，将展示首次将老龄研究发现应用于临床的结果。这些更具翻译性的会议将由直接关注该领域快速发展领域的重要基础进展的会议补充，例如细胞稳态机制和健康衰老的保守机制。我们相信，所有研讨会的主题都是及时的，应该会刺激讨论、合作努力和开发可能的治疗靶点。

 DESCRIPTION (provided by applicant): We are requesting funds to support the 45th Annual Meeting of the American Aging Association to be held June 3rd to June 6th at the Edgewater Hotel and Bell Harbor Conference Center, Seattle, Washington. This meeting is one of the premier meetings for biogerontological research and is the only annual meeting sponsored by a professional membership organization in the United States that limits its focus to biomedical issues in aging. The theme of the meeting is "Targeting Aging: The Ultimate in Preventative Medicine". Dr. Matt Kaeberlein, President of AGE, together with the AGE Program Committee (Drs. Anson, Buffenstein, Nelson, Perez-Olsen, and Promislow), Session Chairs, and the AGE Executive Board organize the scientific program. The overall objective is to convene scientists and trainees from multiple disciplines in a forum for presentation and critical debate of the lates discoveries in aging research and to stimulate forward thinking and collaboration among participants. Funds are requested to help cover travel expenses of 1) invited speakers and 2) meritorious junior scientists (students, postdoctoral fellows and junior faculty) who can benefit from exposure to the leaders of the field, present their research findings and have the opportunity to contribute and get feedback from experts in the field. The specific goals of this meeting are a) to assemble a broad-based forum of basic and clinical scientists to present findings that utilize novel methods, uncover new mechanisms and have potential for development of therapeutics that may enhance quality and length of healthy life; b) to highlight important research areas not recently covered at meetings; c) to encourage open discussion and debate; and d) to emphasize integrative and translational research opportunities. The invited speakers include renowned scientists in aging and related disciplines selected for their science and ability to stimulate debate. When selecting session topics, a particular effort was placed on keeping with the meeting theme of aging research as "The Ultimate Preventative Medicine" by highlighting basic research with clear translational potential for improving healthy aging in people. These include recent high profile work on Systemic Factors and Senescence, including circulating hormones and molecules that can perhaps be manipulated therapeutically; an entire session devoted to work aimed at identifying and validating Interventions That Promote Healthy Aging; and a session titled From bench to clinic: Translational approaches to healthy aging that will present results from the first efforts to apply discoveries from aging research in a clinical setting. These more translational sessions will be complemented by sessions focused squarely on important fundamental advances in the fast moving areas of the field such as Mechanisms of Cellular Homeostasis and Conserved mechanisms of healthy aging. We believe that all of the symposia topics are timely, and should stimulate discussion, collaborative endeavors and the development of possible therapeutic targets.