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Pathogen sensing in autoinflammatory and autoimmune disease

Pathogen sensing in autoinflammatory and autoimmune disease
自身炎症和自身免疫性疾病中的病原体传感
批准号:
nhmrc : 637367
负责人:
Dr Ben Croker
金额:
$22.72万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31

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中文摘要
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英文摘要
Mammals have evolved an array of mechanisms to sense microbes. These immune sentinels must distinguish self from non-self to activate an immune response. The initiation, amplification and quenching of an immune response is a carefully orchestrated process that eliminates invading pathogens while minimising collateral damage to host tissues. This research focuses on proteins that restrict immune responses to prevent inflammatory diseases such as rheumatoid arthritis and psoriasis.
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