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中文摘要
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 描述(申请人提供):由于最近的技术进步,最先进的数据收集和分析方法比以往任何时候都发展得更快。这使得药物滥用和艾滋病毒预防研究人员很难跟上最新的研究方法。我们建议继续举办一系列名为创新方法夏季研究所的年度传播会议,旨在为药物滥用和艾滋病毒研究人员提供所需的知识和技能,以便在收集和分析密集纵向数据(ILD)时应用最突出的创新。对ILD的这种关注是为了回应(A)能够收集与健康行为相关的实时、真实世界数据的技术进步(例如,智能手机、可穿戴传感器),以及(B)国家卫生研究院关于移动健康(移动健康)的日益优先的领域。ILD能够对与行为相关的动态过程进行更深入、更细微的研究,并有可能为行为干预的实时交付提供信息。拟议的会议将帮助预防科学家在概念上和实践上了解他们可以在研究中应用的最先进的ILD方法。所有这些会议都将由ILD方法方面的主要专家介绍,并将由与会者亲自进行数据分析和/或样本数据收集。主题包括ILD的收集,用于计划新的ILD研究的功率分析,以及两种现代ILD分析方法,可以帮助研究人员从他们的复杂数据中获得关键知识。在资助的最后一年,我们建议组织一次为期两天的大型顶峰会议,聚集领先的方法学家(包括演讲者和本R13前四年的选定学员)和与ILD合作的药物滥用和艾滋病毒预防研究人员。这些科学家将共同准备建立下一代适应性行为干预。由于数十年来在开发纵向数据创新方法和培训研究人员应用这些方法方面的经验,宾夕法尼亚州立大学方法学中心是唯一有资格组织这一高度专业化和急需的传播活动的机构。
英文摘要
 DESCRIPTION (provided by applicant): Due to recent technological advances, state-of-the art data collection and analysis methods are evolving faster than ever before. This makes it difficult for drug abuse and HIV prevention researchers to keep up with the latest research methods. We propose to continue a series of annual dissemination conferences, called the Summer Institutes on Innovative Methods, which are designed to provide drug abuse and HIV researchers with the knowledge and skills needed to apply the most salient innovations in the collection and analysis of intensive longitudinal data (ILD). This focus on ILD is in response to (a) technological advances that enable the collection of real-time, real-world data related to health behavior (e.g., smart phones, wearable sensors), and (b) the growing priority area at the National Institutes of Health on mHealth (mobile health). ILD enable a deeper, more nuanced study of dynamic processes related to behavior and have the potential to inform the real-time delivery of behavioral interventions. The proposed conferences will help prevention scientists gain conceptual and practical understanding of state-of-the-art ILD methods they can apply in their research. All of these conferences will be presented by leading experts in ILD methods and will feature hands-on data analysis and/or sample data collection by participants. Topics include the collection of ILD, power analysis for planning new ILD studies, and two modern analytic methods for ILD that can help researchers gain critical knowledge from their complex data. In the final year of funding, we propose to organize a large, two-day capstone conference that will bring together leading methodologists (including presenters and selected trainees from the previous four years of this R13) and drug abuse and HIV prevention researchers working with ILD. Together, these scientists will be poised to build the next generation of adaptive behavioral interventions. Due to decades of experience both in developing innovative methods for longitudinal data and in training researchers to apply those methods, the Methodology Center at Penn State is uniquely qualified to organize this highly specialized, greatly needed dissemination activity.
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Promoting Rapid Uptake of Multilevel Latent Class Modeling via Best Practices: Investigating Heterogeneity in Daily Substance Use Patterns
Prevention and Methodology Training
Age-Varying Effects in the Epidemiology of Drug Abuse
Age-Varying Effects in the Epidemiology of Drug Abuse
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