University of Kansas Training Grant in Nephrology

描述（由申请人提供）：该项目认识到对高技能的医学博士和博士研究人员的持续需求，以解决慢性肾脏疾病在我国迅速增长的冲击，并通过每年容纳两名博士后研究员，与国际公认和美国国立卫生研究院资助的导师在高度整合的跨学科环境中进行肾脏研究方法和项目的强化培训，以满足这一需求。研究培训持续2-3年。对于医学博士学员，研究培训与一年的临床培训相结合，在临床医师导师的指导下，他们使用定量推理和实验室方法来解决肾脏疾病造成的医疗问题，以确保有资格获得肾脏病委员会的认证。目前的研究领域包括人类肾脏疾病的分子遗传学和发病机制，最先进的受体和信号转导生物化学，肾脏发育生物学，代谢性骨病的分子决定因素，肾脏疾病和高血压的临床决策分析和结局研究，上皮运输和代谢。在成功完成奖学金后，学员将准备接受学术部门或医学和/或基础科学研究所的职位，在那里他们可以从事独立的研究事业。

DESCRIPTION (provided by applicant): This program recognizes the continuing need for highly skilled M.D. and Ph.D. researchers to address the burgeoning onslaught of chronic renal diseases descending on our Nation and is designed to address that need by accommodating two post-doctoral fellows each year for intensive training in renal research methods and projects with internationally recognized and NIH-funded mentors working in a highly integrated interdisciplinary environment. Research training lasts 2-3 years. For M.D. trainees, research training is interfaced with a year of clinical training, under the guidance of master clinician preceptors who use quantitative reasoning and laboratory methods to solve medical problems created by renal disease, to insure eligibility for Nephrology Board certification. Current researc areas include the molecular genetics and pathogenesis of human renal diseases, state-of-the-art receptor and signal transduction biochemistry, the biology of kidney developmental, molecular determinants of metabolic bone disease, clinical decision analysis and outcomes research for kidney diseases and hypertension, and epithelial transport and metabolism. Upon successful completion of the fellowship, the trainees will be prepared to accept positions in academic departments or institutes of medicine and/or basic science where they can pursue independent research careers.