Recent Frontiers and Advances in Drug Addiction (IDARS Conference)

 本申请寻求NIDA和NIAAA的共同支持，以使美国科学家能够参加将于2015年8月18日至21日在澳大利亚悉尼威斯汀酒店举行的第五届国际药物滥用研究学会（IDARS）会议。酒精、精神兴奋剂（如甲基苯丙胺）、摇头丸（摇头丸）和其他特制药物（如伽马-羟丁酸和浴盐）、大麻、处方阿片类药物和溶剂/吸入剂/麻醉剂是北美、中美洲、南美洲、欧洲和亚洲滥用最广泛的一些药物，过去二十年来，这些药物的滥用急剧增加。IDARS会议被认为是一个科学论坛，在全世界传播SUD研究的生物医学方面。主要目的是将基础科学家与临床研究者/研究人员聚集在一起，整合来自两个领域的专业知识和科学发现，并促进我们对SUD不同细胞和分子机制的作用的理解和研究。目前和未来的研究挑战是了解哪些特定的细胞系统发生分子变化，以影响导致成瘾和酗酒的动机系统的耐受性和依赖性。因此，本次会议将涵盖分子和细胞生物学，生物行为和临床研究，以及流行病学。将特别强调未来治疗策略的转化研究;将高度鼓励治疗研究人员的参与。药物使用障碍是全球性问题。由于地理上的隔离和缺乏国际一级的交流，世界一个地区的脆弱性和治疗目标的重要研究成果无法应用于世界其他地区。因此，IDARS会议的具体目标是将国际社会的基础科学家和临床研究人员聚集在一起，深入了解和了解CNS作用药物，滥用药物和药物成瘾治疗的新概念。此前IDARS的举办地包括中美洲（墨西哥梅里达，2007年8月14日至17日;墨西哥墨西哥城，2013年4月15日至19日）、亚洲（大韩民国首尔，2009年8月17日至21日）和中东（土耳其伊斯坦布尔，2011年8月23日至26日）。2015年IDARS会议将于8月18日至21日在澳大利亚悉尼威斯汀酒店举行。会议论文摘要将发表在《药物和酒精研究杂志》上。

 DESCRIPTION (provided by applicant): This application seeks shared support from NIDA and NIAAA to enable U.S. scientists to attend the 5th International Drug Abuse Research Society (IDARS) Conference to be held August 18 - 21, 2015, at the Westin Hotel in Sydney, Australia. Alcohol, psychostimulants such as methamphetamine, MDMA (Ecstasy), and other designer drugs such as GHB and bath salt, marijuana, prescription opioids, and solvents/inhalants/anesthetics are some of the most widely abused drugs in North America, Central America, South America, Europe and Asia, and their abuse has dramatically increased over the past two decades. The IDARS Conference is conceived as a scientific forum for disseminating biomedical aspects of SUD research worldwide. The main purpose is to bring basic scientists together with clinical investigators/researchers to integrate expertise and scientific findings from both domains and facilitate our understanding and study of the role of different cellular and molecular mechanisms of SUDs. The current and future research challenge is to understand which specific cellular systems undergo molecular changes to influence tolerance and dependence in motivational systems that lead to addiction and alcoholism. Therefore, this conference will cover molecular and cellular biology, biobehavioral and clinical research, and epidemiology. Particular emphasis will be given to translational research for future treatment strategies; participation by treatment researchers will be highly encouraged. Substance use disorders are global problems. Geographic separation and a lack of communication at the international level hinder the application of important research findings of vulnerability and treatment targets from one part of the world to other parts of the world. Thus, the IDARS Meeting has the specific aim to bring together basic scientists and clinical investigators from the international community to provide an in-depth understanding and current knowledge of new conceptual insights into CNS-acting drugs, drugs of abuse, and drug addiction treatments. Prior IDARS venues have included, Central America (Merida, Mexico, August 14 - 17, 2007; Mexico City, Mexico, April 15 - 19, 2013), Asia (Seoul, Republic of Korea, August 17 - 21, 2009), and the Middle East (Istanbul, Turkey, August 23 - 26, 2011). The 2015 IDARS Conference will be held August 18 - 21, at the Westin Hotel in Sydney, Australia. Abstracts of Conference proceedings will be published in the Journal of Drug and Alcohol Research.