Genomics of rapid adaptation in the lab and in the wild

实验室和野外快速适应的基因组学

• 批准号: 9071712
• 负责人: Dmitri Petrov
• 金额: $ 71.24万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9071712
• 关键词: Award; Biology; Communicable Diseases; Drosophila genus; Evolution; Funding Opportunities; Genomics; Grant; Heart; Humanities; Malignant Neoplasms; Mutation; Process; Research; Research Personnel; Series; System; Theoretical Studies; Yeasts; genomic data; public health relevance; theories

 DESCRIPTION (provided by applicant): Adaptation is the central concept in evolution and biology in general. I aim to build and quantitative and predictive theory of the adaptive process by focusing on interrelated empirical, computational, and theoretical studies of rapid adaptation in a range of systems. The MIRA grant will be supporting three specific umbrella projects that focus on: (i) inference of the dynamics of adaptation from genomic data, (ii) studies of rapid seasonal adaptation in Drosophila, and (iii) high throughput studies of adaptive mutation in experimental evolution studies in yeast.

 描述（由申请人提供）：适应是进化和生物学的中心概念。我的目标是建立和定量和预测的适应过程的理论，专注于相关的经验，计算和理论研究的快速适应在一系列的系统。MIRA赠款将支持三个具体的伞式项目，重点是：（i）从基因组数据中推断适应的动态，（ii）果蝇快速季节性适应的研究，以及（iii）酵母实验进化研究中适应性突变的高通量研究。