Personalized clinical genomics and epigenomics.

个性化临床基因组学和表观基因组学。

• 批准号: nhmrc : 1061177
• 负责人: Prof Melissa Southey
• 金额: $ 42.08万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/personalized-clinical-genomics-epigenomics/454870
• 关键词: Personalized; clinical; genomics; epigenomics.

Genetic factors responsible for risk of breast and prostate cancer are largely unknown. Mutations in genes currently known to be associated with susceptibility only account for a small proportion of the familial aggregation of these cancers. I will be applying new genetic technology to population-based studies of cancer to identify new genetic and epigenetic markers of cancer risk. I will use this information to improve health care for families with prostate and breast cancer.

导致乳腺癌和前列腺癌风险的遗传因素在很大程度上是未知的。目前已知与易感性相关的基因突变仅占这些癌症家族聚集性的一小部分。我将把新的遗传技术应用于基于人群的癌症研究，以确定癌症风险的新遗传和表观遗传标记。我将利用这些信息来改善前列腺癌和乳腺癌家庭的医疗保健。